Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   WID27_RS09195 Genome accession   NZ_CP149796
Coordinates   2187886..2188551 (+) Length   221 a.a.
NCBI ID   WP_070199587.1    Uniprot ID   A0A1E7M052
Organism   Streptomyces sp. F41     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2182886..2193551
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WID27_RS09185 (WID27_09185) - 2185542..2186513 (+) 972 WP_339152027.1 SDR family oxidoreductase -
  WID27_RS09190 (WID27_09190) - 2186645..2187889 (+) 1245 WP_339152028.1 sensor histidine kinase -
  WID27_RS09195 (WID27_09195) vraR 2187886..2188551 (+) 666 WP_070199587.1 response regulator transcription factor Regulator
  WID27_RS09200 (WID27_09200) - 2188699..2190027 (+) 1329 WP_244209639.1 cytochrome ubiquinol oxidase subunit I -
  WID27_RS09205 (WID27_09205) - 2190093..2190869 (+) 777 WP_339152029.1 cytochrome d ubiquinol oxidase subunit II -
  WID27_RS09210 (WID27_09210) - 2190906..2192033 (-) 1128 WP_070199887.1 AI-2E family transporter -
  WID27_RS09215 (WID27_09215) - 2192218..2192412 (-) 195 WP_019765274.1 DUF3046 domain-containing protein -
  WID27_RS09220 (WID27_09220) - 2192493..2193407 (+) 915 WP_339152030.1 hypothetical protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 24092.74 Da        Isoelectric Point: 5.6792

>NTDB_id=875228 WID27_RS09195 WP_070199587.1 2187886..2188551(+) (vraR) [Streptomyces sp. F41]
MIRVVLADDQTLVRAGFRSILSVEDDIEVVGEAADGEQALALAHEHRPDVVLMDIRMPGTDGLEATRRITTDPRLADVRV
VILTTFDMDDHVYGALRAGASGFLVKDTEPMELLHGVRVVARGDALIAPAVTRRLISEFASRRRQPEPGPRLNALTERER
EVMGLVGAGLSNDEIAARLVLSPATSKTHVSRIMTKLGVRDRAQLVILAYESGMITPGWLA

Nucleotide


Download         Length: 666 bp        

>NTDB_id=875228 WID27_RS09195 WP_070199587.1 2187886..2188551(+) (vraR) [Streptomyces sp. F41]
ATGATCCGCGTAGTGCTGGCCGACGACCAGACGCTGGTACGGGCGGGCTTCCGCTCGATCCTGTCCGTCGAGGACGACAT
CGAGGTCGTCGGCGAGGCCGCCGACGGCGAACAGGCCCTCGCCCTGGCCCACGAGCACCGTCCGGACGTGGTCCTGATGG
ACATCCGGATGCCCGGGACGGACGGCCTGGAGGCCACCCGCCGCATCACCACCGATCCGCGCCTGGCGGACGTCCGGGTC
GTCATCCTGACCACCTTCGACATGGACGACCACGTGTACGGGGCGCTGCGCGCCGGAGCCTCCGGTTTCCTGGTCAAGGA
CACCGAGCCGATGGAGCTGTTGCACGGTGTACGGGTGGTGGCGCGGGGCGACGCTCTGATCGCCCCGGCCGTGACCCGGC
GGCTGATCTCGGAGTTCGCGAGCCGCCGCAGGCAGCCGGAGCCGGGTCCCCGCCTCAACGCCCTGACCGAGCGGGAGCGG
GAGGTCATGGGGCTGGTGGGGGCCGGGCTCTCCAACGACGAGATCGCCGCCCGGCTGGTGCTGAGCCCCGCCACCTCCAA
GACCCATGTCAGCCGGATCATGACGAAGCTCGGCGTGCGCGACCGGGCGCAGCTGGTGATCCTCGCCTACGAGTCGGGCA
TGATCACGCCGGGCTGGCTGGCCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(154-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1E7M052

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.589

96.833

0.403
  degU Bacillus subtilis subsp. subtilis str. 168

37.333

100

0.38