Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   WID27_RS06680 Genome accession   NZ_CP149796
Coordinates   1514882..1515520 (+) Length   212 a.a.
NCBI ID   WP_070200994.1    Uniprot ID   A0A1E7LWG2
Organism   Streptomyces sp. F41     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1509882..1520520
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WID27_RS06660 (WID27_06660) - 1510773..1511573 (+) 801 WP_258467569.1 IclR family transcriptional regulator -
  WID27_RS06665 (WID27_06665) - 1511609..1512292 (-) 684 WP_103417578.1 ABC transporter ATP-binding protein -
  WID27_RS06670 (WID27_06670) - 1512289..1513371 (-) 1083 WP_070201578.1 ABC transporter permease -
  WID27_RS06675 (WID27_06675) - 1513482..1514885 (+) 1404 WP_339151842.1 sensor histidine kinase -
  WID27_RS06680 (WID27_06680) vraR 1514882..1515520 (+) 639 WP_070200994.1 response regulator transcription factor Regulator
  WID27_RS06685 (WID27_06685) - 1515635..1515949 (-) 315 WP_019766325.1 DUF5955 family protein -
  WID27_RS06690 (WID27_06690) - 1516140..1516745 (+) 606 WP_070200993.1 nucleotidyltransferase family protein -
  WID27_RS06695 (WID27_06695) aceB 1517014..1518633 (+) 1620 WP_339151843.1 malate synthase A -

Sequence

Protein


Download         Length: 212 a.a.        Molecular weight: 22106.39 Da        Isoelectric Point: 6.3423

>NTDB_id=875221 WID27_RS06680 WP_070200994.1 1514882..1515520(+) (vraR) [Streptomyces sp. F41]
MSDAIRLLLADDHPVVRAGLRAVLDTEPDFRVAGEAATAEEAVALAAAGGFDVVLMDLQFGPGPGMHGSEATAAITAVPG
GPRVLILTTYDSDADILAAVEAGASGYLLKDAPPQELAAAVRTAAAGRSALAPSVAHRLMDRMRTPAEALTRRELEVLQL
VGEGLSNLRISKELFLSQATVKSHLVHIYAKLGVDSRTAAVAAATARRLIRR

Nucleotide


Download         Length: 639 bp        

>NTDB_id=875221 WID27_RS06680 WP_070200994.1 1514882..1515520(+) (vraR) [Streptomyces sp. F41]
GTGAGCGACGCCATCCGGCTGCTGCTGGCGGACGACCACCCTGTCGTACGGGCGGGGCTGCGCGCGGTCCTGGACACCGA
GCCGGACTTCCGGGTCGCGGGCGAGGCGGCCACCGCCGAGGAGGCCGTGGCGCTGGCGGCGGCGGGCGGCTTCGACGTCG
TCCTGATGGACCTCCAGTTCGGTCCGGGCCCCGGAATGCACGGCTCCGAGGCCACGGCGGCGATCACCGCCGTGCCCGGC
GGCCCCCGGGTCCTGATCCTCACCACGTACGACTCCGACGCGGACATCCTGGCGGCGGTGGAGGCGGGGGCGAGCGGCTA
TCTGCTGAAGGACGCGCCCCCGCAGGAGCTGGCGGCGGCGGTGCGGACGGCCGCGGCGGGCCGCTCGGCGCTCGCGCCCT
CGGTGGCGCACCGGCTGATGGACCGGATGCGGACGCCCGCCGAGGCGCTGACGCGGCGGGAGCTGGAGGTGCTGCAACTG
GTCGGGGAGGGGCTGTCGAACCTGCGCATCAGCAAGGAGCTGTTCCTCAGCCAGGCCACGGTCAAGTCCCACCTGGTGCA
CATCTACGCGAAGCTGGGCGTCGACTCCCGTACGGCCGCGGTCGCGGCGGCGACGGCCCGCAGGCTGATCCGCCGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(8-121)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1E7LWG2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.441

99.528

0.373
  degU Bacillus subtilis subsp. subtilis str. 168

35

100

0.363