Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   WHL52_RS17935 Genome accession   NZ_CP149576
Coordinates   3389645..3390280 (-) Length   211 a.a.
NCBI ID   WP_003243201.1    Uniprot ID   O32197
Organism   Bacillus subtilis strain DSM 10     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3384645..3395280
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHL52_RS17915 yvzF 3385702..3385887 (-) 186 WP_003244599.1 YvzF family protein -
  WHL52_RS17920 gerAA 3386005..3387453 (+) 1449 WP_009969097.1 spore germination receptor protein GerAA -
  WHL52_RS17925 gerAB 3387422..3388519 (+) 1098 WP_009968145.1 spore germination receptor protein GerAB -
  WHL52_RS17930 gerAC 3388516..3389637 (+) 1122 WP_009968146.1 spore germination receptor protein GerAC -
  WHL52_RS17935 vraR 3389645..3390280 (-) 636 WP_003243201.1 two-component system response regulator LiaR Regulator
  WHL52_RS17940 liaS 3390258..3391340 (-) 1083 WP_003244464.1 two-component system sensor histidine kinase LiaS -
  WHL52_RS17945 liaF 3391337..3392062 (-) 726 WP_003242605.1 LiaRS two-component regulatory system accessory protein LiaF -
  WHL52_RS17950 liaG 3392096..3392968 (-) 873 WP_003244420.1 DUF4097 domain-containing protein -
  WHL52_RS17955 liaH 3393069..3393746 (-) 678 WP_003243047.1 PspA/IM30 family protein -
  WHL52_RS17960 liaI 3393773..3394153 (-) 381 WP_003243447.1 cell envelope stress-induced membrane anchor protein LiaI -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23124.76 Da        Isoelectric Point: 4.9049

>NTDB_id=875010 WHL52_RS17935 WP_003243201.1 3389645..3390280(-) (vraR) [Bacillus subtilis strain DSM 10]
MIRVLLIDDHEMVRMGLAAFLEAQPDIEVIGEASDGSEGVRLAVELSPDVILMDLVMEGMDGIEATKQICRELSDPKIIV
LTSFIDDDKVYPVIEAGALSYLLKTSKAAEIADAIRAASKGEPKLESKVAGKVLSRLRHSGENALPHESLTKRELEILCL
IAEGKTNKEIGEELFITIKTVKTHITNILSKLDVSDRTQAAVYAHRNHLVN

Nucleotide


Download         Length: 636 bp        

>NTDB_id=875010 WHL52_RS17935 WP_003243201.1 3389645..3390280(-) (vraR) [Bacillus subtilis strain DSM 10]
GTGATTCGAGTATTATTGATTGATGATCATGAAATGGTCAGAATGGGGCTCGCGGCTTTTTTGGAGGCGCAGCCCGATAT
TGAAGTCATCGGCGAAGCATCGGACGGCAGCGAAGGTGTTCGGCTTGCTGTGGAACTGTCGCCTGATGTCATTTTAATGG
ACCTTGTCATGGAGGGCATGGATGGCATTGAAGCTACAAAGCAAATTTGCCGGGAGCTTTCCGACCCGAAAATTATTGTG
CTCACTAGCTTCATTGATGATGACAAAGTGTACCCGGTTATTGAAGCTGGCGCGCTCAGCTATCTGTTGAAAACCTCAAA
AGCGGCAGAAATCGCCGATGCCATCCGCGCCGCAAGCAAGGGAGAGCCGAAGCTGGAGTCAAAAGTGGCGGGAAAAGTAT
TATCCAGGCTGCGCCACTCAGGTGAAAACGCGCTCCCGCATGAATCGCTTACAAAACGGGAGCTCGAAATACTCTGCCTG
ATCGCAGAAGGAAAGACAAACAAAGAAATAGGCGAGGAACTGTTTATTACGATTAAAACAGTCAAAACACATATTACGAA
TATTTTATCAAAGCTGGATGTCAGTGACCGGACGCAGGCGGCGGTGTACGCACACCGAAATCATCTCGTGAATTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O32197

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.857

99.526

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

38.565

100

0.408