Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   RE438_RS06080 Genome accession   NZ_CP133557
Coordinates   1174295..1174978 (+) Length   227 a.a.
NCBI ID   WP_048559561.1    Uniprot ID   A0A2B5NX33
Organism   Bacillus wiedmannii strain EPS29     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1169295..1179978
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RE438_RS06060 (RE438_06030) - 1170361..1172007 (+) 1647 WP_048559563.1 peptide ABC transporter substrate-binding protein -
  RE438_RS06065 (RE438_06035) - 1172035..1172238 (-) 204 WP_000559978.1 hypothetical protein -
  RE438_RS06070 (RE438_06040) spx 1172833..1173228 (+) 396 WP_000258267.1 transcriptional regulator Spx -
  RE438_RS06075 (RE438_06045) - 1173278..1173952 (-) 675 WP_000362605.1 TerC family protein -
  RE438_RS06080 (RE438_06050) mecA 1174295..1174978 (+) 684 WP_048559561.1 adaptor protein MecA Regulator
  RE438_RS06085 (RE438_06055) - 1175051..1176595 (+) 1545 WP_048559560.1 cardiolipin synthase -
  RE438_RS06090 (RE438_06060) - 1176676..1177920 (+) 1245 WP_048559559.1 competence protein CoiA -
  RE438_RS06095 (RE438_06065) pepF 1177971..1179797 (+) 1827 WP_048559558.1 oligoendopeptidase F Regulator

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 27012.08 Da        Isoelectric Point: 3.9987

>NTDB_id=874837 RE438_RS06080 WP_048559561.1 1174295..1174978(+) (mecA) [Bacillus wiedmannii strain EPS29]
MDIERINDHTMKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPLWIQVQAVDKGIEVLVTRAEL
SKDGQKLELPIGVDKIIDIPLDEGIESLFQQELVEEVEEQAGTNFNEDGTFGFLIKFNDFEDVISLSHRLIFEDIKDELY
SFENRYYVYVEFDEVLHDEEEIDRILSIVLEYGEESTLTIHRVSEYGKQIVKERALETIRNNFPAKT

Nucleotide


Download         Length: 684 bp        

>NTDB_id=874837 RE438_RS06080 WP_048559561.1 1174295..1174978(+) (mecA) [Bacillus wiedmannii strain EPS29]
TTGGATATTGAAAGAATTAATGACCATACGATGAAATTTTTTATTACGTACATTGATATAGAGGATAGAGGGTTTAATCG
TGAAGAAATTTGGTATGACCGCGAACGAAGTGAAGAGCTCTTTTGGGAGATGATGGACGAAGCACGTGATCATGATGATT
TCTTTATCGATGGACCGTTATGGATTCAAGTGCAAGCAGTCGATAAAGGGATTGAAGTACTTGTAACGAGAGCAGAGCTT
TCAAAGGATGGACAAAAGCTAGAACTACCAATAGGTGTAGATAAAATTATAGACATTCCTCTAGATGAAGGCATTGAATC
ATTATTCCAGCAAGAATTAGTGGAAGAGGTAGAAGAACAAGCAGGAACAAACTTTAACGAAGATGGTACGTTTGGCTTTT
TAATTAAGTTTAATGATTTTGAAGATGTCATTTCATTAAGCCACCGTCTTATCTTTGAAGATATAAAAGATGAGCTGTAT
TCATTTGAGAACCGCTATTATGTATATGTGGAATTCGATGAAGTGCTACATGATGAAGAAGAAATTGATCGTATTTTAAG
TATTGTTTTAGAATACGGAGAAGAATCAACTTTAACAATTCATCGTGTAAGTGAGTATGGGAAACAAATTGTGAAAGAGC
GTGCGCTTGAAACAATTCGCAATAATTTTCCTGCTAAAACGTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2B5NX33

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

55.702

100

0.559