Detailed information NTG0874613

Bioinformatically predicted

Overview

• Name: comFA/cflA
• Type: Machinery gene
• Locus tag: RDV58_RS08715
• Genome accession: NZ_CP133475
• Coordinates: 1760909..1762210 (-)
• Length: 433 a.a.
• NCBI ID: WP_002279927.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain LMG 14558
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1755909..1767210

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RDV58_RS08690 (RDV58_08675)	-	1755967..1756602 (+)	636	WP_002263021.1	hypothetical protein	-
RDV58_RS08695 (RDV58_08680)	-	1756682..1758382 (-)	1701	WP_002263022.1	zinc ribbon domain-containing protein	-
RDV58_RS08700 (RDV58_08685)	-	1758402..1759496 (-)	1095	WP_002266342.1	hypothetical protein	-
RDV58_RS08705 (RDV58_08690)	hpf	1759620..1760168 (-)	549	WP_002263024.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
RDV58_RS08710 (RDV58_08695)	-	1760247..1760912 (-)	666	WP_002270131.1	ComF family protein	-
RDV58_RS08715 (RDV58_08700)	comFA/cflA	1760909..1762210 (-)	1302	WP_002279927.1	DEAD/DEAH box helicase	Machinery gene
RDV58_RS08720 (RDV58_08705)	-	1762283..1762912 (+)	630	WP_002263027.1	YigZ family protein	-
RDV58_RS08725 (RDV58_08710)	cysK	1763003..1763929 (+)	927	WP_002279926.1	cysteine synthase A	-
RDV58_RS08730 (RDV58_08715)	-	1764263..1765354 (-)	1092	WP_002263029.1	glycerol dehydrogenase	-
RDV58_RS08735 (RDV58_08720)	-	1765392..1766060 (-)	669	WP_002279925.1	fructose-6-phosphate aldolase	-

Sequence

Protein

• Length: 433 a.a.
• Molecular weight: 49481.72 Da
• Isoelectric Point: 9.9950

>NTDB_id=874613 RDV58_RS08715 WP_002279927.1 1760909..1762210(-) (comFA/cflA) [Streptococcus mutans strain LMG 14558]
MENLENYYGRLLTENQMNSDLKKQAKILPAMIKKPHYFICNRCGSQNNLGNALPDGSIYCRACLVFGRLTNRDSLYYFEQ
KPFPKGQVLRWQGQLTPFQQEVSRGLKKSVCHKENMLIHAVTGAGKTEMIYETLASILNQGGAVALASPRIDVCIELYKR
LSRDFSCPISLLYGESEAYERSPLVIATTHQLLKFYRAFDLLIIDEVDAFPFVDNKMLYYAVDHCLKSDGVKVFLTATST
DQLDKQVKQGKLKKLHLARRFHANPLVVPKPIWLNLSLERLQRGKLPRSFLQQIRIQRQIQFPLLIFFPNIEDGLTFAKS
LQTYLPNEKIDFVSSLTTDRLEKVENFRKGNTQILVSTTILERGVTFPCVDVFVMMSNHYLFTKSSLVQIAGRVGRSADR
PDGKLLFFHNGMNRAMKKAIMEIKTMNKKGGFA

Nucleotide

• Length: 1302 bp

>NTDB_id=874613 RDV58_RS08715 WP_002279927.1 1760909..1762210(-) (comFA/cflA) [Streptococcus mutans strain LMG 14558]
ATGGAGAATTTAGAGAATTATTATGGCCGCCTCTTGACCGAGAATCAAATGAACAGTGATTTGAAAAAGCAAGCTAAAAT
CTTGCCAGCTATGATAAAAAAACCGCATTACTTTATCTGCAATCGTTGCGGCAGTCAGAACAATCTTGGTAATGCTTTGC
CGGATGGATCTATCTACTGTCGAGCTTGTCTTGTCTTTGGACGTCTTACTAACAGGGACAGTCTTTATTATTTTGAGCAA
AAGCCTTTTCCAAAGGGTCAGGTCTTAAGGTGGCAAGGGCAATTAACCCCTTTTCAGCAGGAAGTTTCCCGTGGTTTAAA
AAAGAGTGTTTGCCATAAGGAAAATATGCTTATTCATGCTGTAACAGGTGCAGGCAAAACGGAGATGATTTATGAAACTC
TGGCCAGCATTCTCAATCAAGGGGGTGCGGTTGCACTTGCTAGTCCTCGCATTGATGTCTGCATAGAACTGTATAAACGT
TTAAGTCGTGACTTTTCTTGTCCTATCAGTCTTTTGTATGGAGAGTCAGAAGCTTATGAACGCAGTCCATTAGTGATTGC
AACCACGCATCAACTTTTGAAATTTTACCGAGCTTTTGATTTGTTAATTATTGATGAAGTAGATGCCTTTCCTTTTGTTG
ACAATAAGATGCTCTATTATGCTGTAGATCATTGTCTGAAATCAGATGGTGTCAAAGTATTTTTGACTGCAACTTCGACT
GACCAATTAGACAAACAGGTTAAGCAAGGGAAGCTAAAAAAACTGCATTTAGCCAGACGATTTCATGCCAATCCCTTAGT
TGTTCCCAAGCCAATTTGGTTGAATTTATCTCTTGAAAGATTACAAAGAGGTAAATTACCGCGCTCTTTTTTACAGCAGA
TAAGAATTCAAAGGCAGATTCAATTCCCTCTTTTGATCTTTTTTCCGAATATTGAAGATGGTTTAACCTTTGCTAAATCA
CTGCAAACCTATCTTCCAAATGAGAAAATTGATTTTGTTTCCAGCTTGACAACAGATCGTTTAGAAAAAGTCGAAAATTT
TAGAAAAGGAAACACACAAATTTTGGTTTCAACAACGATTTTAGAGAGGGGAGTCACTTTTCCTTGTGTAGATGTTTTTG
TCATGATGAGCAACCATTATCTGTTCACCAAAAGTTCTCTGGTACAGATTGCTGGTCGTGTGGGACGCTCTGCCGATAGA
CCAGATGGAAAATTACTTTTCTTTCATAATGGAATGAACAGAGCCATGAAAAAGGCCATTATGGAAATCAAGACTATGAA
CAAAAAAGGAGGTTTTGCATGA

Domains

Predicted by InterproScan.

• Type III restriction enzyme, res subunit (ResIII) (94-168)

• Helicase conserved C-terminal domain (Helicase_C) (296-397)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFA/cflA	Streptococcus pneumoniae Rx1	59.251	98.614	0.584
comFA/cflA	Streptococcus pneumoniae D39	59.251	98.614	0.584
comFA/cflA	Streptococcus pneumoniae R6	59.251	98.614	0.584
comFA/cflA	Streptococcus pneumoniae TIGR4	59.251	98.614	0.584
comFA/cflA	Streptococcus mitis NCTC 12261	58.548	98.614	0.577
comFA/cflA	Streptococcus mitis SK321	58.548	98.614	0.577
comFA	Lactococcus lactis subsp. cremoris KW2	51.777	90.993	0.471
comFA	Latilactobacillus sakei subsp. sakei 23K	38.695	99.076	0.383