Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   WG890_RS09665 Genome accession   NZ_CP149449
Coordinates   1976411..1977067 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain JX21CE33     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1971411..1982067
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WG890_RS09630 (WG890_09630) dcyD 1972291..1973277 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  WG890_RS09635 (WG890_09635) tcyL 1973292..1973960 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  WG890_RS09640 (WG890_09640) tcyN 1973957..1974709 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WG890_RS09645 (WG890_09645) sdiA 1974939..1975661 (+) 723 WP_001154265.1 transcriptional regulator SdiA -
  WG890_RS09650 (WG890_09650) yecF 1975728..1975952 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  WG890_RS09655 (WG890_09655) yecU 1975939..1976115 (-) 177 WP_001307856.1 protein YecU -
  WG890_RS09660 (WG890_09660) - 1976198..1976269 (-) 72 Protein_1886 transcriptional regulator -
  WG890_RS09665 (WG890_09665) letA 1976411..1977067 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  WG890_RS09670 (WG890_09670) uvrC 1977064..1978896 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  WG890_RS09675 (WG890_09675) pgsA 1978953..1979501 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WG890_RS09695 (WG890_09695) yecA 1980151..1980816 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=874052 WG890_RS09665 WP_000611328.1 1976411..1977067(+) (letA) [Escherichia coli strain JX21CE33]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=874052 WG890_RS09665 WP_000611328.1 1976411..1977067(+) (letA) [Escherichia coli strain JX21CE33]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482