Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   WDR05_RS17000 Genome accession   NZ_CP149444
Coordinates   3257347..3257982 (-) Length   211 a.a.
NCBI ID   WP_003243201.1    Uniprot ID   O32197
Organism   Bacillus subtilis strain HC-9     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3252347..3262982
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WDR05_RS16980 (WDR05_16960) yvzF 3253404..3253589 (-) 186 WP_003244599.1 YvzF family protein -
  WDR05_RS16985 (WDR05_16965) gerAA 3253707..3255155 (+) 1449 WP_003243555.1 spore germination receptor protein GerAA -
  WDR05_RS16990 (WDR05_16970) gerAB 3255124..3256221 (+) 1098 WP_009968145.1 spore germination receptor protein GerAB -
  WDR05_RS16995 (WDR05_16975) gerAC 3256218..3257339 (+) 1122 WP_003243203.1 spore germination receptor protein GerAC -
  WDR05_RS17000 (WDR05_16980) vraR 3257347..3257982 (-) 636 WP_003243201.1 two-component system response regulator LiaR Regulator
  WDR05_RS17005 (WDR05_16985) liaS 3257960..3259042 (-) 1083 WP_003228512.1 two-component system sensor histidine kinase LiaS -
  WDR05_RS17010 (WDR05_16990) liaF 3259039..3259764 (-) 726 WP_003228510.1 LiaRS two-component regulatory system accessory protein LiaF -
  WDR05_RS17015 (WDR05_16995) liaG 3259798..3260670 (-) 873 WP_003228508.1 DUF4097 domain-containing protein -
  WDR05_RS17020 (WDR05_17000) liaH 3260771..3261448 (-) 678 WP_003228506.1 stress responsive protein LiaH -
  WDR05_RS17025 (WDR05_17005) liaI 3261475..3261855 (-) 381 WP_003228504.1 cell envelope stress-induced membrane anchor protein LiaI -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23124.76 Da        Isoelectric Point: 4.9049

>NTDB_id=873936 WDR05_RS17000 WP_003243201.1 3257347..3257982(-) (vraR) [Bacillus subtilis strain HC-9]
MIRVLLIDDHEMVRMGLAAFLEAQPDIEVIGEASDGSEGVRLAVELSPDVILMDLVMEGMDGIEATKQICRELSDPKIIV
LTSFIDDDKVYPVIEAGALSYLLKTSKAAEIADAIRAASKGEPKLESKVAGKVLSRLRHSGENALPHESLTKRELEILCL
IAEGKTNKEIGEELFITIKTVKTHITNILSKLDVSDRTQAAVYAHRNHLVN

Nucleotide


Download         Length: 636 bp        

>NTDB_id=873936 WDR05_RS17000 WP_003243201.1 3257347..3257982(-) (vraR) [Bacillus subtilis strain HC-9]
GTGATTCGAGTATTATTGATTGATGATCATGAAATGGTCAGAATGGGGCTCGCGGCTTTTTTGGAGGCGCAGCCCGATAT
TGAAGTCATCGGCGAAGCATCGGACGGCAGCGAAGGTGTTCGGCTTGCTGTGGAACTGTCGCCTGATGTCATTTTAATGG
ACCTTGTCATGGAGGGCATGGATGGCATTGAAGCTACAAAGCAAATTTGCCGGGAGCTTTCCGACCCGAAAATTATTGTG
CTCACTAGCTTCATTGATGATGACAAAGTGTACCCGGTTATTGAAGCTGGCGCGCTCAGCTATCTGTTGAAAACCTCAAA
AGCGGCAGAAATCGCCGATGCCATCCGCGCCGCAAGCAAGGGAGAGCCGAAGCTGGAGTCAAAAGTGGCGGGAAAAGTAT
TATCCAGGCTGCGCCACTCAGGTGAAAACGCGCTCCCGCATGAATCGCTTACAAAACGGGAGCTCGAAATACTCTGCCTG
ATCGCAGAAGGAAAGACAAACAAAGAAATAGGCGAGGAACTGTTTATTACGATTAAAACAGTCAAAACACATATTACGAA
TATTTTATCAAAGCTGGATGTCAGTGACCGGACGCAGGCGGCGGTGTACGCACACCGAAATCATCTCGTGAATTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O32197

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.857

99.526

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

38.565

100

0.408