Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   WHU28_RS11095 Genome accession   NZ_CP148507
Coordinates   2197858..2198514 (+) Length   218 a.a.
NCBI ID   WP_000611338.1    Uniprot ID   -
Organism   Escherichia coli strain Z1323CEC0001     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2192858..2203514
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHU28_RS11065 (WHU28_11055) dcyD 2193737..2194723 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  WHU28_RS11070 (WHU28_11060) tcyL 2194738..2195406 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  WHU28_RS11075 (WHU28_11065) tcyN 2195403..2196155 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WHU28_RS11080 (WHU28_11070) sdiA 2196385..2197107 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  WHU28_RS11085 (WHU28_11075) yecF 2197175..2197399 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  WHU28_RS11090 (WHU28_11080) yecU 2197386..2197562 (-) 177 WP_001307856.1 protein YecU -
  WHU28_RS11095 (WHU28_11085) letA 2197858..2198514 (+) 657 WP_000611338.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  WHU28_RS11100 (WHU28_11090) uvrC 2198511..2200343 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  WHU28_RS11105 (WHU28_11095) pgsA 2200400..2200948 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WHU28_RS11125 (WHU28_11115) - 2201644..2202384 (-) 741 WP_069722689.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23908.65 Da        Isoelectric Point: 6.9614

>NTDB_id=872864 WHU28_RS11095 WP_000611338.1 2197858..2198514(+) (letA) [Escherichia coli strain Z1323CEC0001]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNSVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=872864 WHU28_RS11095 WP_000611338.1 2197858..2198514(+) (letA) [Escherichia coli strain Z1323CEC0001]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATTCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.691

94.954

0.491
  letA Legionella pneumophila strain ERS1305867

51.691

94.954

0.491