Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   WHU64_RS10885 Genome accession   NZ_CP148498
Coordinates   2161669..2162325 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain Z1323CEC0002     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2156669..2167325
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHU64_RS10855 (WHU64_10835) dcyD 2157548..2158534 (+) 987 WP_001128218.1 D-cysteine desulfhydrase -
  WHU64_RS10860 (WHU64_10840) tcyL 2158549..2159217 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  WHU64_RS10865 (WHU64_10845) tcyN 2159214..2159966 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WHU64_RS10870 (WHU64_10850) sdiA 2160196..2160918 (+) 723 WP_024231281.1 transcriptional regulator SdiA -
  WHU64_RS10875 (WHU64_10855) yecF 2160986..2161210 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  WHU64_RS10880 (WHU64_10860) yecU 2161197..2161373 (-) 177 WP_000590347.1 protein YecU -
  WHU64_RS10885 (WHU64_10865) letA 2161669..2162325 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  WHU64_RS10890 (WHU64_10870) uvrC 2162322..2164154 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  WHU64_RS10895 (WHU64_10875) pgsA 2164211..2164759 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WHU64_RS10915 (WHU64_10895) - 2165452..2166191 (-) 740 Protein_2131 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=872780 WHU64_RS10885 WP_000611328.1 2161669..2162325(+) (letA) [Escherichia coli strain Z1323CEC0002]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=872780 WHU64_RS10885 WP_000611328.1 2161669..2162325(+) (letA) [Escherichia coli strain Z1323CEC0002]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482