Detailed information NTG0872300

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: RB649_RS09650
• Genome accession: NZ_CP133179
• Coordinates: 1776504..1777508 (-)
• Length: 334 a.a.
• NCBI ID: WP_011174226.1
• Uniprot ID: Q72GH5
• Organism: Thermus thermophilus HB27
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1771504..1782508

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RB649_RS09615 (RB649_09615)	hisG	1771976..1772596 (+)	621	WP_011174220.1	ATP phosphoribosyltransferase	-
RB649_RS09620 (RB649_09620)	trmH	1772593..1773177 (+)	585	WP_011174221.1	tRNA (guanosine(18)-2'-O)-methyltransferase TrmH	-
RB649_RS09625 (RB649_09625)	-	1773167..1773406 (-)	240	WP_008630920.1	hypothetical protein	-
RB649_RS09630 (RB649_09630)	-	1773408..1773596 (-)	189	WP_011174222.1	hypothetical protein	-
RB649_RS09635 (RB649_09635)	-	1773586..1774542 (-)	957	WP_011174223.1	branched-chain amino acid transaminase	-
RB649_RS09640 (RB649_09640)	-	1774529..1775482 (-)	954	WP_011174224.1	hydrogen peroxide-inducible genes activator	-
RB649_RS09645 (RB649_09645)	-	1775592..1776500 (+)	909	WP_011174225.1	manganese catalase family protein	-
RB649_RS09650 (RB649_09650)	dprA	1776504..1777508 (-)	1005	WP_011174226.1	DNA-processing protein DprA	Machinery gene
RB649_RS09655 (RB649_09655)	era	1777593..1778498 (+)	906	WP_008630929.1	GTPase Era	-
RB649_RS09660 (RB649_09660)	-	1778543..1779430 (+)	888	WP_011174227.1	acyltransferase	-
RB649_RS09670 (RB649_09670)	-	1779626..1780804 (-)	1179	WP_011174228.1	site-specific integrase	-

Sequence

Protein

• Length: 334 a.a.
• Molecular weight: 36235.18 Da
• Isoelectric Point: 6.8891

>NTDB_id=872300 RB649_RS09650 WP_011174226.1 1776504..1777508(-) (dprA) [Thermus thermophilus HB27]
MDPLALALLPGIGPKRLLEVLKAEDPLGFLRERFPEAWRHLPEAEAQAERERRRAEALGVRLLGLWEEGFPEGLKALPQP
PTHLYLKGELPPEREAVALVGTRRASPWALAFARKLARELSEAGLWVVSGLARGIDREAHLGALEAGGRTLGVLGSALDR
VYPPENRPLAQRMDLLSEFPFGTGPKPEFFPRRNRLIAGLCRAVVVVEAPLDSGALITARHALELGKEVLAVPGRPMDER
SLGANRLIQDGAYPVLSAEDVLSYLGMSARPKPLPGLSPEEEALYALLQEKKEALPEALAMALGIPPERVLSLLTLLELK
GLARALPGGRYGPG

Nucleotide

• Length: 1005 bp

>NTDB_id=872300 RB649_RS09650 WP_011174226.1 1776504..1777508(-) (dprA) [Thermus thermophilus HB27]
GTGGACCCCTTGGCCCTCGCCCTCCTCCCGGGCATCGGCCCCAAGCGGCTTTTGGAGGTCCTAAAGGCGGAGGACCCTCT
GGGCTTCCTGCGGGAGCGCTTCCCCGAGGCCTGGCGGCACCTCCCCGAGGCCGAGGCCCAGGCGGAAAGGGAGAGGCGGC
GCGCCGAGGCCCTAGGGGTGCGCCTCCTGGGTCTCTGGGAGGAGGGCTTCCCCGAGGGGCTGAAGGCGCTTCCCCAGCCG
CCCACCCACCTCTACCTGAAGGGGGAGCTTCCCCCGGAAAGGGAGGCGGTGGCCCTCGTGGGCACGCGCCGGGCCTCCCC
TTGGGCCCTGGCCTTTGCCCGGAAGCTCGCCCGGGAGCTTTCCGAGGCCGGGCTCTGGGTGGTCTCGGGCCTCGCCCGGG
GCATAGACCGGGAGGCCCACCTCGGGGCCCTCGAGGCCGGGGGGCGCACCCTGGGCGTCTTGGGAAGCGCCCTGGACCGG
GTCTACCCCCCGGAAAACCGCCCTTTGGCCCAACGGATGGACCTCCTCTCCGAGTTCCCCTTCGGCACCGGGCCCAAGCC
CGAGTTCTTTCCCCGGCGGAACCGCCTCATCGCCGGGCTTTGCCGGGCGGTGGTCGTGGTGGAGGCCCCCCTGGACTCCG
GGGCCCTCATCACCGCCCGCCACGCCCTGGAGCTCGGCAAGGAGGTGCTGGCCGTGCCCGGAAGGCCCATGGACGAGCGT
TCTCTGGGAGCCAACCGCCTCATCCAGGACGGGGCCTACCCGGTGCTCTCCGCCGAGGATGTCCTCTCCTATCTGGGAAT
GTCCGCAAGGCCCAAGCCCCTCCCGGGCCTCTCCCCGGAGGAGGAGGCCCTTTACGCCCTCCTGCAGGAAAAGAAGGAGG
CGCTCCCCGAGGCCCTGGCCATGGCCCTGGGGATCCCCCCGGAGCGGGTGCTCTCCCTTCTCACCCTTTTGGAGCTAAAG
GGCCTGGCCCGGGCCCTCCCGGGAGGGCGCTACGGGCCAGGCTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (56-255)

• DprA winged helix domain (DprA_WH) (269-329)

3D structure

• AlphaFold DB: Q72GH5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Thermus thermophilus HB27	100	100	1
dprA	Vibrio campbellii strain DS40M4	38.547	100	0.413
dprA	Vibrio cholerae strain A1552	37.255	100	0.398
dprA	Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539	45.392	87.725	0.398