Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   WHU71_RS10160 Genome accession   NZ_CP148440
Coordinates   1999772..2000428 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain Z1323CEC0011     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1994772..2005428
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHU71_RS10125 (WHU71_10125) dcyD 1995652..1996638 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  WHU71_RS10130 (WHU71_10130) tcyL 1996653..1997321 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  WHU71_RS10135 (WHU71_10135) tcyN 1997318..1998070 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WHU71_RS10140 (WHU71_10140) sdiA 1998300..1999022 (+) 723 WP_032200101.1 transcriptional regulator SdiA -
  WHU71_RS10145 (WHU71_10145) yecF 1999089..1999313 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  WHU71_RS10150 (WHU71_10150) yecU 1999300..1999476 (-) 177 WP_001307856.1 protein YecU -
  WHU71_RS10155 (WHU71_10155) - 1999559..1999630 (-) 72 Protein_1970 transcriptional regulator -
  WHU71_RS10160 (WHU71_10160) letA 1999772..2000428 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  WHU71_RS10165 (WHU71_10165) uvrC 2000425..2002257 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  WHU71_RS10170 (WHU71_10170) pgsA 2002314..2002862 (+) 549 WP_032200177.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WHU71_RS10190 (WHU71_10190) yecA 2003512..2004177 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=872022 WHU71_RS10160 WP_000611335.1 1999772..2000428(+) (letA) [Escherichia coli strain Z1323CEC0011]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=872022 WHU71_RS10160 WP_000611335.1 1999772..2000428(+) (letA) [Escherichia coli strain Z1323CEC0011]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486