Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   WHU40_RS15690 Genome accession   NZ_CP148435
Coordinates   3145068..3145724 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain Z1323CEC0012     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3140068..3150724
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHU40_RS15655 (WHU40_15655) dcyD 3140948..3141934 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  WHU40_RS15660 (WHU40_15660) tcyL 3141949..3142617 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  WHU40_RS15665 (WHU40_15665) tcyN 3142614..3143366 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WHU40_RS15670 (WHU40_15670) sdiA 3143596..3144318 (+) 723 WP_032200101.1 transcriptional regulator SdiA -
  WHU40_RS15675 (WHU40_15675) yecF 3144385..3144609 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  WHU40_RS15680 (WHU40_15680) yecU 3144596..3144772 (-) 177 WP_001307856.1 protein YecU -
  WHU40_RS15685 (WHU40_15685) - 3144855..3144926 (-) 72 Protein_3050 transcriptional regulator -
  WHU40_RS15690 (WHU40_15690) letA 3145068..3145724 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  WHU40_RS15695 (WHU40_15695) uvrC 3145721..3147553 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  WHU40_RS15700 (WHU40_15700) pgsA 3147610..3148158 (+) 549 WP_032200177.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WHU40_RS15720 (WHU40_15720) yecA 3148808..3149473 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=871971 WHU40_RS15690 WP_000611335.1 3145068..3145724(+) (letA) [Escherichia coli strain Z1323CEC0012]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=871971 WHU40_RS15690 WP_000611335.1 3145068..3145724(+) (letA) [Escherichia coli strain Z1323CEC0012]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486