Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   WHU00_RS22565 Genome accession   NZ_CP148427
Coordinates   4465504..4466160 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain Z1323CEC0013     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4460504..4471160
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHU00_RS22530 (WHU00_22530) dcyD 4461384..4462370 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  WHU00_RS22535 (WHU00_22535) tcyL 4462385..4463053 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  WHU00_RS22540 (WHU00_22540) tcyN 4463050..4463802 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WHU00_RS22545 (WHU00_22545) sdiA 4464032..4464754 (+) 723 WP_032200101.1 transcriptional regulator SdiA -
  WHU00_RS22550 (WHU00_22550) yecF 4464821..4465045 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  WHU00_RS22555 (WHU00_22555) yecU 4465032..4465208 (-) 177 WP_001307856.1 protein YecU -
  WHU00_RS22560 (WHU00_22560) - 4465291..4465362 (-) 72 Protein_4399 transcriptional regulator -
  WHU00_RS22565 (WHU00_22565) letA 4465504..4466160 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  WHU00_RS22570 (WHU00_22570) uvrC 4466157..4467989 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  WHU00_RS22575 (WHU00_22575) pgsA 4468046..4468594 (+) 549 WP_032200177.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WHU00_RS22595 (WHU00_22595) - 4469292..4470032 (-) 741 WP_338929561.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=871903 WHU00_RS22565 WP_000611335.1 4465504..4466160(+) (letA) [Escherichia coli strain Z1323CEC0013]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=871903 WHU00_RS22565 WP_000611335.1 4465504..4466160(+) (letA) [Escherichia coli strain Z1323CEC0013]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486