Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   WHU39_RS18600 Genome accession   NZ_CP148426
Coordinates   3656889..3657545 (-) Length   218 a.a.
NCBI ID   WP_000611338.1    Uniprot ID   -
Organism   Escherichia coli strain Z1323CEC0014     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3651889..3662545
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHU39_RS18570 (WHU39_18570) yecA 3653140..3653805 (-) 666 WP_000847880.1 UPF0149 family protein YecA -
  WHU39_RS18590 (WHU39_18590) pgsA 3654455..3655003 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WHU39_RS18595 (WHU39_18595) uvrC 3655060..3656892 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  WHU39_RS18600 (WHU39_18600) letA 3656889..3657545 (-) 657 WP_000611338.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  WHU39_RS18605 (WHU39_18605) yecU 3657841..3658017 (+) 177 WP_001307856.1 protein YecU -
  WHU39_RS18610 (WHU39_18610) yecF 3658004..3658228 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  WHU39_RS18615 (WHU39_18615) sdiA 3658296..3659018 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  WHU39_RS18620 (WHU39_18620) tcyN 3659248..3660000 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WHU39_RS18625 (WHU39_18625) tcyL 3659997..3660665 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  WHU39_RS18630 (WHU39_18630) dcyD 3660680..3661666 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23908.65 Da        Isoelectric Point: 6.9614

>NTDB_id=871805 WHU39_RS18600 WP_000611338.1 3656889..3657545(-) (letA) [Escherichia coli strain Z1323CEC0014]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNSVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=871805 WHU39_RS18600 WP_000611338.1 3656889..3657545(-) (letA) [Escherichia coli strain Z1323CEC0014]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATTCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.691

94.954

0.491
  letA Legionella pneumophila strain ERS1305867

51.691

94.954

0.491