Detailed information NTG0871292

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SHJJP9002_RS04560
• Genome accession: NZ_CP133006
• Coordinates: 983737..984780 (+)
• Length: 347 a.a.
• NCBI ID: WP_046837882.1
• Uniprot ID: A0A1S2MGQ4
• Organism: Staphylococcus casei strain SCK7
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 978737..989780

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SHJJP9002_RS04535 (SHJJP9002_000905)	-	979806..980525 (+)	720	WP_069824827.1	glutamine amidotransferase	-
SHJJP9002_RS04540 (SHJJP9002_000906)	-	980618..981604 (-)	987	WP_046837886.1	aromatic acid exporter family protein	-
SHJJP9002_RS04545 (SHJJP9002_000907)	map	981779..982531 (+)	753	WP_069824826.1	type I methionyl aminopeptidase	-
SHJJP9002_RS04550 (SHJJP9002_000908)	-	982636..983022 (+)	387	WP_069824825.1	hypothetical protein	-
SHJJP9002_RS04555 (SHJJP9002_000909)	liaF	983039..983740 (+)	702	WP_069824824.1	cell wall-active antibiotics response protein LiaF	-
SHJJP9002_RS04560 (SHJJP9002_000910)	vraS	983737..984780 (+)	1044	WP_046837882.1	sensor histidine kinase	Regulator
SHJJP9002_RS04565 (SHJJP9002_000911)	vraR	984770..985399 (+)	630	WP_046837881.1	response regulator transcription factor	Regulator
SHJJP9002_RS04570 (SHJJP9002_000912)	-	985596..986741 (-)	1146	WP_069824823.1	YihY/virulence factor BrkB family protein	-
SHJJP9002_RS04575 (SHJJP9002_000913)	-	986957..987241 (-)	285	WP_046837879.1	hypothetical protein	-
SHJJP9002_RS04580 (SHJJP9002_000914)	-	987241..987711 (-)	471	WP_069824822.1	low molecular weight protein-tyrosine-phosphatase	-
SHJJP9002_RS04585 (SHJJP9002_000915)	-	987845..988051 (+)	207	WP_256121787.1	DUF1128 family protein	-
SHJJP9002_RS04590 (SHJJP9002_000916)	-	988067..989308 (+)	1242	WP_341636897.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40023.42 Da
• Isoelectric Point: 6.2448

>NTDB_id=871292 SHJJP9002_RS04560 WP_046837882.1 983737..984780(+) (vraS) [Staphylococcus casei strain SCK7]
MNHYLRAIGSMLILVYSTFFAIFFIDKVFVNIMYFQGMFYTQIFGIPVLLFLNLLVILLCIIVGSVLAYKINQQNHWLQE
QIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESQLEAPLDQQIPVLEKMIQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVVDLQKKVPMKVVHDI
EEFKVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNRTDYLLLRIQDNGKGFNVDEKAEQSYGLKNMRERALEIGAT
YHIVSLPDSGTRIEVKAPLNKEDSYAD

Nucleotide

• Length: 1044 bp

>NTDB_id=871292 SHJJP9002_RS04560 WP_046837882.1 983737..984780(+) (vraS) [Staphylococcus casei strain SCK7]
ATGAATCACTACTTAAGGGCAATAGGATCCATGTTAATTTTAGTCTATAGTACATTTTTCGCGATATTCTTTATTGATAA
AGTCTTTGTAAACATCATGTACTTTCAAGGTATGTTTTATACACAAATATTTGGAATACCAGTTTTACTATTTTTAAATT
TATTGGTTATATTGCTCTGTATTATAGTAGGATCAGTATTAGCGTATAAAATTAATCAACAGAACCATTGGTTACAAGAA
CAAATTGAACGTTCTATAGAAGGTCAAACTGTAGGGATTAATGATCAAAATATAGAGTTGTATAATGAAACGATAGAATT
ATATCAAACACTTGTACCTTTAAACCAAGAAGTGCACAAATTAAGAATGAAAACACAAAATTTAACGAATGAATCTTATA
ATATTAATGATGTAAAGGTTAAAAAGATTATAGAAGATGAACGACAAAGACTAGCACGTGAATTACATGATTCTGTAAGC
CAACAATTATTTGCCGCAAGTATGATGCTTTCTGCTATCAAAGAATCCCAATTAGAAGCGCCTTTGGATCAACAAATCCC
AGTACTTGAAAAGATGATACAAGACTCTCAATTAGAGATGAGAGCACTACTATTACACTTAAGACCACTGGGCTTAAAAG
ATAAATCGTTAGGTGAAGGGATTAAAGATTTAGTTGTAGACCTACAGAAAAAAGTGCCAATGAAAGTTGTCCATGATATC
GAAGAGTTTAAAGTACCAAAGGGTATTGAAGATCATTTGTTTAGAATCACACAAGAAGCAATTTCTAATACTTTGAGACA
TTCTAAGGGCACTAAGGTTACGATTGAATTGTTTAATAGAACAGATTATTTACTATTGCGTATACAAGATAATGGTAAAG
GATTTAATGTAGATGAAAAGGCTGAACAAAGTTATGGGTTGAAAAATATGAGAGAACGCGCATTAGAAATTGGCGCTACA
TATCATATTGTATCTTTACCAGACTCAGGAACAAGGATAGAAGTTAAGGCACCATTAAATAAGGAGGATTCATATGCCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A1S2MGQ4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	88.184	100	0.882