Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   SHJJP9001_RS00170 Genome accession   NZ_CP132999
Coordinates   42754..44103 (-) Length   449 a.a.
NCBI ID   WP_020368079.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain SEA37     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 41104..50954 42754..44103 within 0


Gene organization within MGE regions


Location: 41104..50954
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SHJJP9001_RS00165 (SHJJP9001_000033) ccrB 41104..42732 (-) 1629 WP_002495147.1 recombinase family protein Machinery gene
  SHJJP9001_RS00170 (SHJJP9001_000034) ccrA 42754..44103 (-) 1350 WP_020368079.1 recombinase family protein Machinery gene
  SHJJP9001_RS00175 (SHJJP9001_000035) - 44337..46130 (-) 1794 WP_020368078.1 DUF927 domain-containing protein -
  SHJJP9001_RS00180 (SHJJP9001_000036) - 46130..46426 (-) 297 WP_000221967.1 single-stranded DNA-binding protein -
  SHJJP9001_RS00185 (SHJJP9001_000037) - 46598..48181 (+) 1584 WP_001551935.1 hypothetical protein -
  SHJJP9001_RS00190 (SHJJP9001_000038) - 48253..49185 (+) 933 WP_000364405.1 hypothetical protein -
  SHJJP9001_RS00195 (SHJJP9001_000039) - 49611..49988 (+) 378 WP_000687965.1 hypothetical protein -
  SHJJP9001_RS00200 (SHJJP9001_000040) - 50457..50954 (+) 498 WP_000051479.1 hypothetical protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52505.24 Da        Isoelectric Point: 9.8772

>NTDB_id=871251 SHJJP9001_RS00170 WP_020368079.1 42754..44103(-) (ccrA) [Staphylococcus epidermidis strain SEA37]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQITQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVKNGLQEKAKQGRLITTHAPFGYDYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDDTFINRQPYQVRNIIMNPNYCGRVINQYGQFDNMFPSIVSANV
YEQAQRLRSQKQTKQTPSDNQLKQKIKCPCCNATLTNMTVRKKNHILRYYVCPKNLNASRFVCDFKGINAQTLEDKVLKV
CQDFYQDHHIYAKIKNAIDKRLKRQRNTETHHTLTQEKLIEKLAQGIIDAETFRKQMQSLHQQPQRITSISEHQIQHTIQ
NIIQKRFTLNILYPYIETIHIAKDKNLIGIYFKNEPLNIVNQTMQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=871251 SHJJP9001_RS00170 WP_020368079.1 42754..44103(-) (ccrA) [Staphylococcus epidermidis strain SEA37]
ATGAAACAAGTTATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATAACACAATTAATTCAACAAGGACAATGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACTTACCATGTTCATATCTTAAGCGTACATGATGGTTATTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCAGATAATATTGGAGAAC
AAGTCAAAAATGGCCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACACATGCACCTTTTGGCTACGACTATCAC
AACGGAACATTCATCATCAATCAAAATGAATCACCAACGGTGAAGGCTGTATTCAATTATTACATTAAAGGCCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATGATACGTTCATCAATCGACAACCTTATCAAGTTCGTAATATTATCATGA
ACCCTAATTATTGTGGTCGTGTTATCAACCAATACGGTCAATTCGACAATATGTTCCCTTCTATTGTTTCAGCAAATGTA
TATGAACAAGCGCAGAGACTTCGATCGCAAAAACAAACCAAACAGACACCTTCAGATAATCAACTAAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCGTTAGAAAAAAGAATCATATATTACGTTACTACGTCTGTCCTA
AAAACTTGAATGCTTCACGCTTTGTCTGTGATTTCAAAGGCATCAATGCACAGACATTGGAAGATAAAGTATTAAAAGTG
TGCCAAGACTTTTATCAAGACCACCATATCTACGCAAAAATTAAAAATGCGATTGACAAACGCTTAAAAAGACAACGAAA
CACAGAAACACATCACACACTGACTCAAGAAAAACTAATAGAAAAGTTAGCCCAAGGCATCATCGATGCAGAAACGTTCA
GAAAACAAATGCAATCATTACATCAACAACCGCAACGCATCACATCCATCAGTGAGCATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCTTATATTGAAACCATTCACATTGCGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCTCTCAATATCGTCAATCAAACCATGCAATCATCAATTGCATAA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase (Recombinase)

(169-250)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-322)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus N315

92.205

100

0.922
  ccrA Staphylococcus aureus COL

75.278

100

0.753