Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   WHU26_RS03395 Genome accession   NZ_CP148391
Coordinates   725950..726606 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain Z1323HEC0010     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 720950..731606
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHU26_RS03360 (WHU26_03360) dcyD 721830..722816 (+) 987 WP_001128219.1 D-cysteine desulfhydrase -
  WHU26_RS03365 (WHU26_03365) tcyL 722831..723499 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  WHU26_RS03370 (WHU26_03370) tcyN 723496..724248 (+) 753 WP_137566493.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WHU26_RS03375 (WHU26_03375) sdiA 724478..725200 (+) 723 WP_001154267.1 transcriptional regulator SdiA -
  WHU26_RS03380 (WHU26_03380) yecF 725267..725491 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  WHU26_RS03385 (WHU26_03385) yecU 725478..725654 (-) 177 WP_000590347.1 protein YecU -
  WHU26_RS03390 (WHU26_03390) - 725737..725808 (-) 72 Protein_658 transcriptional regulator -
  WHU26_RS03395 (WHU26_03395) letA 725950..726606 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  WHU26_RS03400 (WHU26_03400) uvrC 726603..728435 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  WHU26_RS03405 (WHU26_03405) pgsA 728492..729040 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WHU26_RS03425 (WHU26_03425) - 730033..730314 (+) 282 WP_001303543.1 hypothetical protein -
  WHU26_RS03430 (WHU26_03430) - 730503..730643 (-) 141 WP_000078920.1 Hok/Gef family protein -
  WHU26_RS03435 (WHU26_03435) - 730835..731095 (-) 261 WP_000488112.1 ogr/Delta-like zinc finger family protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=871183 WHU26_RS03395 WP_000611335.1 725950..726606(+) (letA) [Escherichia coli strain Z1323HEC0010]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=871183 WHU26_RS03395 WP_000611335.1 725950..726606(+) (letA) [Escherichia coli strain Z1323HEC0010]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486