Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   WHU55_RS09275 Genome accession   NZ_CP148385
Coordinates   1916828..1918660 (+) Length   610 a.a.
NCBI ID   WP_001283421.1    Uniprot ID   P0A8G1
Organism   Escherichia coli strain Z1323HEC0011     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1911828..1923660
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHU55_RS09235 (WHU55_09235) dcyD 1912054..1913040 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  WHU55_RS09240 (WHU55_09240) tcyL 1913055..1913723 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  WHU55_RS09245 (WHU55_09245) tcyN 1913720..1914472 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WHU55_RS09250 (WHU55_09250) sdiA 1914702..1915424 (+) 723 WP_001154260.1 transcriptional regulator SdiA -
  WHU55_RS09255 (WHU55_09255) yecF 1915492..1915716 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  WHU55_RS09260 (WHU55_09260) yecU 1915703..1915879 (-) 177 WP_000590344.1 protein YecU -
  WHU55_RS09265 (WHU55_09265) - 1915917..1916033 (-) 117 WP_001302039.1 hypothetical protein -
  WHU55_RS09270 (WHU55_09270) letA 1916175..1916831 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  WHU55_RS09275 (WHU55_09275) uvrC 1916828..1918660 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  WHU55_RS09280 (WHU55_09280) pgsA 1918717..1919265 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WHU55_RS09300 (WHU55_09300) yecA 1919915..1920580 (+) 666 WP_000847902.1 UPF0149 family protein YecA -
  WHU55_RS09305 (WHU55_09305) tyrP 1920642..1921853 (-) 1212 WP_000797573.1 tyrosine transporter TyrP -
  WHU55_RS09310 (WHU55_09310) yecH 1922044..1922283 (+) 240 WP_000377225.1 YecH family metal-binding protein -
  WHU55_RS09315 (WHU55_09315) ftnA 1922321..1922818 (-) 498 WP_000917208.1 non-heme ferritin -
  WHU55_RS09320 (WHU55_09320) yecR 1922989..1923312 (-) 324 WP_001237866.1 YecR-like lipofamily protein -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68188.03 Da        Isoelectric Point: 9.3685

>NTDB_id=871129 WHU55_RS09275 WP_001283421.1 1916828..1918660(+) (uvrC) [Escherichia coli strain Z1323HEC0011]
MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=871129 WHU55_RS09275 WP_001283421.1 1916828..1918660(+) (uvrC) [Escherichia coli strain Z1323HEC0011]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAAAACCGTAACCAGCCAGCCAGGCGTTTATCGCATGTACGATGCTGG
TGGTACGGTTATCTATGTCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGTAGCAACCTCGCTTCGC
GCAAAACCGAAGCGCTGGTCGCCCAGATCCAGCAAATTGATGTAACGGTTACTCATACAGAAACCGAAGCGCTGTTGCTG
GAACACAACTACATCAAACTCTATCAGCCGCGTTACAACGTTTTGCTACGCGATGATAAATCTTATCCCTTTATCTTCCT
GAGTGGCGATACCCATCCGCGTCTGGCGATGCATCGTGGTGCGAAGCATGCCAAAGGTGAATATTTCGGCCCGTTCCCGA
ATGGCTATGCCGTACGTGAAACACTGGCGCTACTGCAAAAGATATTCCCCATTCGCCAGTGCGAAAATAGTGTTTATCGC
AATCGCTCGCGTCCGTGTCTGCAATATCAAATAGGGCGCTGTCTGGGACCGTGCGTTGAAGGACTGGTGAGTGAAGAAGA
ATACGCTCAGCAGGTCGAGTATGTGCGCCTGTTTTTGTCTGGTAAAGATGATCAGGTGCTTACGCAACTCATTAGCCGTA
TGGAAACTGCCAGTCAGAATCTGGAGTTTGAAGAAGCGGCACGTATTCGCGACCAAATTCAGGCGGTGCGACGCGTCACC
GAAAAACAGTTTGTGTCCAATACCGGCGACGACCTTGACGTTATTGGTGTGGCGTTCGATGCGGGCATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGCAAAGTGCTCGGCAGCCGCAGCTATTTCCCGAAAGTGCCGGGCGGTACGGAACTGAGCG
AGGTGGTAGAAACCTTCGTAGGTCAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCAAGATTAATGTTCAAACCAAACC
TCGCGGCGATAGGGCGCGTTATCTGAAACTCGCGCGCACCAATGCGGCGACGGCCTTAACCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGGCTGACCGCGCTTGCCAGCGTGTTGAAATTGCCGGAAGTGAAGCGGATGGAGTGCTTTGACATC
AGCCATACCATGGGCGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCTAACGGCCCGCTGCGTGCGGAGTATCGGCG
CTATAACATTACAGGCATCACGCCGGGCGATGATTATGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCCA
TTGACGACAGTAAGATCCCGGATGTGATCCTTATCGACGGCGGCAAAGGCCAGCTTGCGCAGGCGAAAAATGTCTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCGCTGCTACTTGGCGTTGCCAAAGGTGCAGATCGTAAGGCTGGACTGGA
AACGCTGTTCTTTGAGCCGGAAGGTGAGGGATTTAGTTTGCCGCCAGATTCACCCGCGCTGCATGTTATCCAGCATATTC
GCGATGAATCACATGATCACGCGATTGGCGGGCACCGTAAAAAACGGGCGAAAGTCAAAAATACCAGTTCCCTGGAAACC
ATTGAAGGCGTCGGGCCAAAACGTCGGCAAATGTTGTTGAAATATATGGGCGGTTTGCAAGGTTTACGTAACGCCAGCGT
CGAGGAAATTGCAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-237)

Helix-hairpin-helix domain (HHH_5)

(558-609)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-542)

GIY-YIG catalytic domain (GIY-YIG)

(18-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0A8G1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.891

99.508

0.377
  uvrC Streptococcus pneumoniae R6

37.562

99.508

0.374
  uvrC Streptococcus pneumoniae D39

37.562

99.508

0.374