Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   WHU48_RS09240 Genome accession   NZ_CP148382
Coordinates   1940831..1941487 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain Z1323HEC0016     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1935831..1946487
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHU48_RS09210 (WHU48_09210) dcyD 1936710..1937696 (+) 987 WP_001128230.1 D-cysteine desulfhydrase -
  WHU48_RS09215 (WHU48_09215) tcyL 1937711..1938379 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  WHU48_RS09220 (WHU48_09220) tcyN 1938376..1939128 (+) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WHU48_RS09225 (WHU48_09225) sdiA 1939358..1940080 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  WHU48_RS09230 (WHU48_09230) yecF 1940148..1940372 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  WHU48_RS09235 (WHU48_09235) yecU 1940359..1940535 (-) 177 WP_001307856.1 protein YecU -
  WHU48_RS09240 (WHU48_09240) letA 1940831..1941487 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  WHU48_RS09245 (WHU48_09245) uvrC 1941484..1943316 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  WHU48_RS09250 (WHU48_09250) pgsA 1943373..1943921 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WHU48_RS09270 (WHU48_09270) yecA 1944571..1945236 (+) 666 WP_000847877.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=871048 WHU48_RS09240 WP_000611328.1 1940831..1941487(+) (letA) [Escherichia coli strain Z1323HEC0016]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=871048 WHU48_RS09240 WP_000611328.1 1940831..1941487(+) (letA) [Escherichia coli strain Z1323HEC0016]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCACAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482