Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   WHU33_RS04645 Genome accession   NZ_CP148374
Coordinates   904075..904731 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain Z1323HEC0108     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 899075..909731
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHU33_RS04615 (WHU33_04615) yecA 900326..900991 (-) 666 WP_335266659.1 UPF0149 family protein YecA -
  WHU33_RS04635 (WHU33_04635) pgsA 901641..902189 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WHU33_RS04640 (WHU33_04640) uvrC 902246..904078 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  WHU33_RS04645 (WHU33_04645) letA 904075..904731 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  WHU33_RS04650 (WHU33_04650) - 904873..904944 (+) 72 Protein_917 transcriptional regulator -
  WHU33_RS04655 (WHU33_04655) yecU 905027..905203 (+) 177 WP_000590347.1 protein YecU -
  WHU33_RS04660 (WHU33_04660) yecF 905190..905414 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  WHU33_RS04665 (WHU33_04665) sdiA 905481..906203 (-) 723 WP_001154271.1 transcriptional regulator SdiA -
  WHU33_RS04670 (WHU33_04670) tcyN 906433..907185 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WHU33_RS04675 (WHU33_04675) tcyL 907182..907850 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  WHU33_RS04680 (WHU33_04680) dcyD 907865..908851 (-) 987 WP_001128219.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=870857 WHU33_RS04645 WP_000611335.1 904075..904731(-) (letA) [Escherichia coli strain Z1323HEC0108]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=870857 WHU33_RS04645 WP_000611335.1 904075..904731(-) (letA) [Escherichia coli strain Z1323HEC0108]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486