Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   WHU37_RS01745 Genome accession   NZ_CP148349
Coordinates   329660..330316 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain Z1323HEC0399     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 324660..335316
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHU37_RS01715 (WHU37_01705) dcyD 325539..326525 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  WHU37_RS01720 (WHU37_01710) tcyL 326540..327208 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  WHU37_RS01725 (WHU37_01715) tcyN 327205..327957 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WHU37_RS01730 (WHU37_01720) sdiA 328187..328909 (+) 723 WP_001154283.1 transcriptional regulator SdiA -
  WHU37_RS01735 (WHU37_01725) yecF 328977..329201 (-) 225 WP_000106476.1 DUF2594 family protein YecF -
  WHU37_RS01740 (WHU37_01730) yecU 329188..329364 (-) 177 WP_001307856.1 protein YecU -
  WHU37_RS01745 (WHU37_01735) letA 329660..330316 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  WHU37_RS01750 (WHU37_01740) uvrC 330313..332145 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  WHU37_RS01755 (WHU37_01745) pgsA 332202..332750 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WHU37_RS01775 (WHU37_01765) - 333446..334186 (-) 741 WP_022581686.1 hypothetical protein -
  WHU37_RS01780 (WHU37_01770) - 334267..334743 (+) 477 Protein_345 Arm DNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=870531 WHU37_RS01745 WP_000611328.1 329660..330316(+) (letA) [Escherichia coli strain Z1323HEC0399]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=870531 WHU37_RS01745 WP_000611328.1 329660..330316(+) (letA) [Escherichia coli strain Z1323HEC0399]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482