Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   WHU51_RS07150 Genome accession   NZ_CP148314
Coordinates   1285476..1286132 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain Z1323MEC0002     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1280476..1291132
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHU51_RS07110 (WHU51_07110) - 1280986..1281246 (+) 261 WP_000488107.1 ogr/Delta-like zinc finger family protein -
  WHU51_RS07115 (WHU51_07115) - 1281436..1281576 (+) 141 WP_000078920.1 Hok/Gef family protein -
  WHU51_RS07120 (WHU51_07120) - 1281766..1282047 (-) 282 WP_071529678.1 hypothetical protein -
  WHU51_RS07140 (WHU51_07140) pgsA 1283042..1283590 (-) 549 WP_001160189.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WHU51_RS07145 (WHU51_07145) uvrC 1283647..1285479 (-) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  WHU51_RS07150 (WHU51_07150) letA 1285476..1286132 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  WHU51_RS07155 (WHU51_07155) - 1286274..1286345 (+) 72 Protein_1412 transcriptional regulator -
  WHU51_RS07160 (WHU51_07160) yecU 1286428..1286604 (+) 177 WP_000590347.1 protein YecU -
  WHU51_RS07165 (WHU51_07165) yecF 1286591..1286815 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  WHU51_RS07170 (WHU51_07170) sdiA 1286882..1287604 (-) 723 WP_001154271.1 transcriptional regulator SdiA -
  WHU51_RS07175 (WHU51_07175) tcyN 1287834..1288586 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WHU51_RS07180 (WHU51_07180) tcyL 1288583..1289251 (-) 669 WP_001158206.1 cystine ABC transporter permease -
  WHU51_RS07185 (WHU51_07185) dcyD 1289266..1290252 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=869880 WHU51_RS07150 WP_000611335.1 1285476..1286132(-) (letA) [Escherichia coli strain Z1323MEC0002]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=869880 WHU51_RS07150 WP_000611335.1 1285476..1286132(-) (letA) [Escherichia coli strain Z1323MEC0002]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486