Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   WHU17_RS13450 Genome accession   NZ_CP148289
Coordinates   2737680..2738336 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain Z1323PEC0008     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2732680..2743336
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHU17_RS13420 (WHU17_13385) yecA 2733931..2734597 (-) 667 Protein_2625 UPF0149 family protein YecA -
  WHU17_RS13440 (WHU17_13405) pgsA 2735246..2735794 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WHU17_RS13445 (WHU17_13410) uvrC 2735851..2737683 (-) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  WHU17_RS13450 (WHU17_13415) letA 2737680..2738336 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  WHU17_RS13455 (WHU17_13420) - 2738478..2738594 (+) 117 WP_001302039.1 hypothetical protein -
  WHU17_RS13460 (WHU17_13425) yecU 2738632..2738808 (+) 177 WP_001342215.1 protein YecU -
  WHU17_RS13465 (WHU17_13430) yecF 2738795..2739019 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  WHU17_RS13470 (WHU17_13435) sdiA 2739087..2739809 (-) 723 WP_001154265.1 transcriptional regulator SdiA -
  WHU17_RS13475 (WHU17_13440) tcyN 2740039..2740791 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WHU17_RS13480 (WHU17_13445) tcyL 2740788..2741456 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  WHU17_RS13485 (WHU17_13450) dcyD 2741471..2742457 (-) 987 WP_001128238.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=869825 WHU17_RS13450 WP_000611328.1 2737680..2738336(-) (letA) [Escherichia coli strain Z1323PEC0008]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=869825 WHU17_RS13450 WP_000611328.1 2737680..2738336(-) (letA) [Escherichia coli strain Z1323PEC0008]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482