Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   WHT88_RS12965 Genome accession   NZ_CP148269
Coordinates   2586186..2586842 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain Z1323PEC0013     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2581186..2591842
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHT88_RS12935 (WHT88_12910) yecA 2582437..2583102 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  WHT88_RS12955 (WHT88_12930) pgsA 2583752..2584300 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WHT88_RS12960 (WHT88_12935) uvrC 2584357..2586189 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  WHT88_RS12965 (WHT88_12940) letA 2586186..2586842 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  WHT88_RS12970 (WHT88_12945) yecU 2587138..2587314 (+) 177 WP_032160694.1 protein YecU -
  WHT88_RS12975 (WHT88_12950) yecF 2587301..2587525 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  WHT88_RS12980 (WHT88_12955) sdiA 2587592..2588314 (-) 723 WP_001154275.1 transcriptional regulator SdiA -
  WHT88_RS12985 (WHT88_12960) tcyN 2588544..2589296 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WHT88_RS12990 (WHT88_12965) tcyL 2589293..2589961 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  WHT88_RS12995 (WHT88_12970) dcyD 2589976..2590962 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=869501 WHT88_RS12965 WP_000611328.1 2586186..2586842(-) (letA) [Escherichia coli strain Z1323PEC0013]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=869501 WHT88_RS12965 WP_000611328.1 2586186..2586842(-) (letA) [Escherichia coli strain Z1323PEC0013]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGCCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482