Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   RAL98_RS00315 Genome accession   NZ_CP132544
Coordinates   35670..36299 (-) Length   209 a.a.
NCBI ID   WP_251518488.1    Uniprot ID   -
Organism   Staphylococcus sp. HKU1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 30670..41299
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RAL98_RS00285 (RAL98_00285) - 30684..31214 (-) 531 WP_251518504.1 acyl-CoA thioesterase -
  RAL98_RS00290 (RAL98_00290) - 31249..32487 (-) 1239 WP_418128816.1 aminopeptidase -
  RAL98_RS00295 (RAL98_00295) - 32501..32683 (-) 183 WP_418129309.1 DUF1128 family protein -
  RAL98_RS00300 (RAL98_00300) - 33277..33741 (+) 465 WP_251942705.1 low molecular weight protein-tyrosine-phosphatase -
  RAL98_RS00305 (RAL98_00305) - 33748..34032 (+) 285 WP_251518492.1 YtxH domain-containing protein -
  RAL98_RS00310 (RAL98_00310) - 34356..35549 (+) 1194 WP_251518490.1 YihY/virulence factor BrkB family protein -
  RAL98_RS00315 (RAL98_00315) vraR 35670..36299 (-) 630 WP_251518488.1 response regulator transcription factor Regulator
  RAL98_RS00320 (RAL98_00320) vraS 36289..37332 (-) 1044 WP_251518486.1 sensor histidine kinase Regulator
  RAL98_RS00325 (RAL98_00325) liaF 37329..38030 (-) 702 WP_251518484.1 cell wall-active antibiotics response protein LiaF -
  RAL98_RS00330 (RAL98_00330) - 38049..38435 (-) 387 WP_251518482.1 hypothetical protein -
  RAL98_RS00335 (RAL98_00335) map 38540..39292 (-) 753 WP_251518480.1 type I methionyl aminopeptidase -
  RAL98_RS00340 (RAL98_00340) - 39459..40445 (+) 987 WP_251518478.1 FUSC family protein -
  RAL98_RS00345 (RAL98_00345) - 40537..41256 (-) 720 WP_251518476.1 type 1 glutamine amidotransferase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23688.22 Da        Isoelectric Point: 4.9144

>NTDB_id=869368 RAL98_RS00315 WP_251518488.1 35670..36299(-) (vraR) [Staphylococcus sp. HKU1]
MPIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGKSGKEAIEKAHELHPDLILMDLLMDDMDGVEATEQVKKDLPHTKVL
MLTSYIEDNEVYRALDSGVDSYILKTTSASDIAEAIRKTHEGESVFEAEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=869368 RAL98_RS00315 WP_251518488.1 35670..36299(-) (vraR) [Staphylococcus sp. HKU1]
ATGCCGATTAAAGTATTATTTGTTGATGATCATGAGATGGTTCGCATTGGTATTTCAAGTTATTTATCTACGCAACCAGA
TATTGAAGTAGTTGGGGAAGGGAAATCTGGTAAAGAAGCAATTGAAAAAGCCCATGAACTTCATCCGGATTTAATTTTAA
TGGATTTGCTCATGGATGACATGGATGGGGTAGAAGCGACAGAACAAGTTAAAAAAGATTTACCTCATACGAAAGTATTG
ATGTTAACAAGTTATATCGAGGATAACGAAGTGTACCGTGCTCTAGATTCTGGCGTTGATAGTTATATCTTAAAGACAAC
GAGTGCGAGTGATATTGCAGAAGCGATTCGTAAAACTCATGAAGGTGAATCAGTCTTTGAAGCAGAAGTGCTCGTGAAAA
TGCGTAATAGAATGAAAAAACGTGCTGAGTTATATGAAATGTTAACTGAACGTGAAATGGAGATACTACTATTAATTGCT
AAAGGTTATTCTAATCAAGAAATTGCAAGCGCCTCACATATTACGATCAAAACGGTTAAAACCCATGTAAGTAATATCTT
AAGTAAACTAGAAGTCCAAGATCGAACACAAGCTGTTATTTATGCTTTCCAACACAACTTAATACAGTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-117)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

90.909

100

0.909
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.388