Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   RAM32_RS06385 Genome accession   NZ_CP132361
Coordinates   1302493..1303062 (+) Length   189 a.a.
NCBI ID   WP_000872881.1    Uniprot ID   -
Organism   Staphylococcus aureus strain UNC_SA56     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1297493..1308062
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RAM32_RS06360 (RAM32_06355) cysE 1298706..1299353 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  RAM32_RS06365 (RAM32_06360) cysS 1299337..1300737 (+) 1401 WP_000631966.1 cysteine--tRNA ligase -
  RAM32_RS06370 (RAM32_06365) - 1300730..1301134 (+) 405 WP_000370185.1 Mini-ribonuclease 3 -
  RAM32_RS06375 (RAM32_06370) rlmB 1301142..1301888 (+) 747 WP_000390329.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  RAM32_RS06380 (RAM32_06375) - 1301888..1302412 (+) 525 WP_000664732.1 NYN domain-containing protein -
  RAM32_RS06385 (RAM32_06380) sigH 1302493..1303062 (+) 570 WP_000872881.1 sigma-70 family RNA polymerase sigma factor Regulator
  RAM32_RS06390 (RAM32_06385) rpmG 1303177..1303320 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  RAM32_RS06395 (RAM32_06390) secE 1303376..1303558 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  RAM32_RS06400 (RAM32_06395) nusG 1303571..1304119 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  RAM32_RS06405 (RAM32_06400) rplK 1304300..1304722 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  RAM32_RS06410 (RAM32_06405) rplA 1304930..1305622 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  RAM32_RS06415 (RAM32_06410) rplJ 1305894..1306394 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  RAM32_RS06420 (RAM32_06415) rplL 1306437..1306805 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  RAM32_RS06425 (RAM32_06420) - 1306980..1307588 (+) 609 WP_000020306.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23096.97 Da        Isoelectric Point: 9.6924

>NTDB_id=868441 RAM32_RS06385 WP_000872881.1 1302493..1303062(+) (sigH) [Staphylococcus aureus strain UNC_SA56]
MKYDLTTQDSTIKRNNAINDKDFEKLVMNLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=868441 RAM32_RS06385 WP_000872881.1 1302493..1303062(+) (sigH) [Staphylococcus aureus strain UNC_SA56]
TTGAAATATGATTTGACAACGCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGAATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTTATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979