Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   QFX49_RS09015 Genome accession   NZ_CP132038
Coordinates   1784435..1785121 (+) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain 1.6     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1779435..1790121
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QFX49_RS08980 yqeH 1779962..1781062 (+) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -
  QFX49_RS08985 aroE 1781076..1781882 (+) 807 WP_000666761.1 shikimate dehydrogenase -
  QFX49_RS08990 yhbY 1781886..1782176 (+) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  QFX49_RS08995 nadD 1782179..1782748 (+) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  QFX49_RS09000 yqeK 1782738..1783322 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  QFX49_RS09005 rsfS 1783323..1783676 (+) 354 WP_001088022.1 ribosome silencing factor -
  QFX49_RS09010 - 1783679..1784395 (+) 717 WP_000084829.1 class I SAM-dependent methyltransferase -
  QFX49_RS09015 comEA 1784435..1785121 (+) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  QFX49_RS09020 - 1785213..1785674 (+) 462 WP_000439693.1 ComE operon protein 2 -
  QFX49_RS09025 comEC 1785679..1787880 (+) 2202 WP_001566051.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  QFX49_RS09030 holA 1787937..1788911 (+) 975 WP_304984666.1 DNA polymerase III subunit delta -
  QFX49_RS09035 rpsT 1788956..1789207 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=866926 QFX49_RS09015 WP_001792568.1 1784435..1785121(+) (comEA) [Staphylococcus aureus strain 1.6]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=866926 QFX49_RS09015 WP_001792568.1 1784435..1785121(+) (comEA) [Staphylococcus aureus strain 1.6]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969