Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   WHO18_RS05245 Genome accession   NZ_CP148128
Coordinates   1009387..1010031 (+) Length   214 a.a.
NCBI ID   WP_003245647.1    Uniprot ID   O07528
Organism   Bacillus subtilis isolate FELIX_MS620     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1004387..1015031
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHO18_RS05230 glpD 1004558..1006225 (+) 1668 WP_003233382.1 glycerol-3-phosphate dehydrogenase -
  WHO18_RS05235 pgcA 1006357..1008102 (+) 1746 WP_003244986.1 phosphoglucomutase -
  WHO18_RS05240 yhcY 1008251..1009390 (+) 1140 WP_003245750.1 two-component system sensor histidine kinase YhcY -
  WHO18_RS05245 vraR 1009387..1010031 (+) 645 WP_003245647.1 two-component system response regulator YhcZ Regulator
  WHO18_RS05250 yhdA 1010028..1010552 (+) 525 WP_003244703.1 FMN-dependent NADPH-azoreductase -
  WHO18_RS05255 yhdB 1010567..1010809 (-) 243 WP_003233373.1 YhdB family protein -
  WHO18_RS05260 yhdC 1011010..1011333 (+) 324 WP_003233371.1 YqzG/YhdC family protein -
  WHO18_RS05265 lytF 1011375..1012841 (-) 1467 WP_003244874.1 peptidoglycan endopeptidase LytF -
  WHO18_RS05270 nsrR 1012994..1013434 (-) 441 WP_003245378.1 nitric oxide-sensing transcriptional repressor NsrR -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24022.59 Da        Isoelectric Point: 6.3034

>NTDB_id=865770 WHO18_RS05245 WP_003245647.1 1009387..1010031(+) (vraR) [Bacillus subtilis isolate FELIX_MS620]
MKIVIADDHHVVRKGLRFFFATQDDIEVVGEAATGLEALRVIEETKPDLVLMDLSMPEMDGIQAIKKAIQQFPDTNIIVL
TSYSDQEHVIPALQAGAKAYQLKDTEPEELVKTRQVHGGEYKLSTAIMPHVLTHMKNQHDPEKEKYYQLTRREKDVLTEI
ANGKSNKEIAAALFISEKTVKTHVSNLLAKLEVADRTQAALFAVKYNLNGEISK

Nucleotide


Download         Length: 645 bp        

>NTDB_id=865770 WHO18_RS05245 WP_003245647.1 1009387..1010031(+) (vraR) [Bacillus subtilis isolate FELIX_MS620]
ATGAAAATTGTCATTGCTGATGATCATCATGTTGTCAGAAAGGGTCTGCGTTTTTTCTTTGCCACCCAGGATGATATTGA
AGTCGTCGGAGAAGCTGCAACTGGATTAGAAGCCCTCCGTGTCATCGAAGAGACAAAGCCGGATCTTGTGCTAATGGATT
TGTCTATGCCCGAGATGGACGGCATTCAAGCCATTAAAAAAGCAATACAGCAATTTCCGGATACGAATATCATTGTGCTG
ACGAGCTACTCTGATCAGGAGCACGTCATCCCCGCGCTTCAGGCAGGCGCGAAGGCGTATCAATTAAAGGATACGGAGCC
CGAGGAATTGGTGAAAACACGACAAGTGCATGGTGGCGAATACAAGCTTTCTACAGCTATTATGCCCCATGTGCTGACAC
ATATGAAAAATCAGCACGACCCGGAAAAAGAAAAATACTATCAATTAACTAGAAGGGAAAAAGACGTTCTGACTGAAATA
GCGAACGGGAAAAGCAATAAAGAAATCGCAGCAGCCTTGTTTATTTCAGAAAAAACAGTAAAAACCCATGTATCGAATCT
TTTAGCAAAACTTGAAGTGGCCGATCGCACGCAAGCAGCGCTTTTCGCAGTGAAATATAACCTGAATGGAGAGATCTCAA
AATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O07528

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.976

97.664

0.439
  degU Bacillus subtilis subsp. subtilis str. 168

38.428

100

0.411