Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   WHO38_RS17930 Genome accession   NZ_CP148124
Coordinates   3393155..3393790 (-) Length   211 a.a.
NCBI ID   WP_003243201.1    Uniprot ID   O32197
Organism   Bacillus subtilis isolate FELIX_MS521     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3388155..3398790
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHO38_RS17910 yvzF 3389212..3389397 (-) 186 WP_003244599.1 YvzF family protein -
  WHO38_RS17915 gerAA 3389515..3390963 (+) 1449 WP_009969097.1 spore germination receptor protein GerAA -
  WHO38_RS17920 gerAB 3390932..3392029 (+) 1098 WP_009968145.1 spore germination receptor protein GerAB -
  WHO38_RS17925 gerAC 3392026..3393147 (+) 1122 WP_009968146.1 spore germination receptor protein GerAC -
  WHO38_RS17930 vraR 3393155..3393790 (-) 636 WP_003243201.1 two-component system response regulator LiaR Regulator
  WHO38_RS17935 liaS 3393768..3394850 (-) 1083 WP_003244464.1 two-component system sensor histidine kinase LiaS -
  WHO38_RS17940 liaF 3394847..3395572 (-) 726 WP_003242605.1 LiaRS two-component regulatory system accessory protein LiaF -
  WHO38_RS17945 liaG 3395606..3396478 (-) 873 WP_003244420.1 DUF4097 domain-containing protein -
  WHO38_RS17950 liaH 3396579..3397256 (-) 678 WP_003243047.1 PspA/IM30 family protein -
  WHO38_RS17955 liaI 3397283..3397663 (-) 381 WP_003243447.1 cell envelope stress-induced membrane anchor protein LiaI -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23124.76 Da        Isoelectric Point: 4.9049

>NTDB_id=865627 WHO38_RS17930 WP_003243201.1 3393155..3393790(-) (vraR) [Bacillus subtilis isolate FELIX_MS521]
MIRVLLIDDHEMVRMGLAAFLEAQPDIEVIGEASDGSEGVRLAVELSPDVILMDLVMEGMDGIEATKQICRELSDPKIIV
LTSFIDDDKVYPVIEAGALSYLLKTSKAAEIADAIRAASKGEPKLESKVAGKVLSRLRHSGENALPHESLTKRELEILCL
IAEGKTNKEIGEELFITIKTVKTHITNILSKLDVSDRTQAAVYAHRNHLVN

Nucleotide


Download         Length: 636 bp        

>NTDB_id=865627 WHO38_RS17930 WP_003243201.1 3393155..3393790(-) (vraR) [Bacillus subtilis isolate FELIX_MS521]
GTGATTCGAGTATTATTGATTGATGATCATGAAATGGTCAGAATGGGGCTCGCGGCTTTTTTGGAGGCGCAGCCCGATAT
TGAAGTCATCGGCGAAGCATCGGACGGCAGCGAAGGTGTTCGGCTTGCTGTGGAACTGTCGCCTGATGTCATTTTAATGG
ACCTTGTCATGGAGGGCATGGATGGCATTGAAGCTACAAAGCAAATTTGCCGGGAGCTTTCCGACCCGAAAATTATTGTG
CTCACTAGCTTCATTGATGATGACAAAGTGTACCCGGTTATTGAAGCTGGCGCGCTCAGCTATCTGTTGAAAACCTCAAA
AGCGGCAGAAATCGCCGATGCCATCCGCGCCGCAAGCAAGGGAGAGCCGAAGCTGGAGTCAAAAGTGGCGGGAAAAGTAT
TATCCAGGCTGCGCCACTCAGGTGAAAACGCGCTCCCGCATGAATCGCTTACAAAACGGGAGCTCGAAATACTCTGCCTG
ATCGCAGAAGGAAAGACAAACAAAGAAATAGGCGAGGAACTGTTTATTACGATTAAAACAGTCAAAACACATATTACGAA
TATTTTATCAAAGCTGGATGTCAGTGACCGGACGCAGGCGGCGGTGTACGCACACCGAAATCATCTCGTGAATTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O32197

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.857

99.526

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

38.565

100

0.408