Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   WHO22_RS17960 Genome accession   NZ_CP148122
Coordinates   3393936..3394571 (-) Length   211 a.a.
NCBI ID   WP_003243201.1    Uniprot ID   O32197
Organism   Bacillus subtilis isolate FELIX_MS513     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3388936..3399571
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHO22_RS17940 yvzF 3389993..3390178 (-) 186 WP_003244599.1 YvzF family protein -
  WHO22_RS17945 gerAA 3390296..3391744 (+) 1449 WP_009969097.1 spore germination receptor protein GerAA -
  WHO22_RS17950 gerAB 3391713..3392810 (+) 1098 WP_009968145.1 spore germination receptor protein GerAB -
  WHO22_RS17955 gerAC 3392807..3393928 (+) 1122 WP_009968146.1 spore germination receptor protein GerAC -
  WHO22_RS17960 vraR 3393936..3394571 (-) 636 WP_003243201.1 two-component system response regulator LiaR Regulator
  WHO22_RS17965 liaS 3394549..3395631 (-) 1083 WP_003244464.1 two-component system sensor histidine kinase LiaS -
  WHO22_RS17970 liaF 3395628..3396353 (-) 726 WP_003242605.1 LiaRS two-component regulatory system accessory protein LiaF -
  WHO22_RS17975 liaG 3396387..3397259 (-) 873 WP_003244420.1 DUF4097 domain-containing protein -
  WHO22_RS17980 liaH 3397360..3398037 (-) 678 WP_003243047.1 PspA/IM30 family protein -
  WHO22_RS17985 liaI 3398064..3398444 (-) 381 WP_003243447.1 cell envelope stress-induced membrane anchor protein LiaI -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23124.76 Da        Isoelectric Point: 4.9049

>NTDB_id=865469 WHO22_RS17960 WP_003243201.1 3393936..3394571(-) (vraR) [Bacillus subtilis isolate FELIX_MS513]
MIRVLLIDDHEMVRMGLAAFLEAQPDIEVIGEASDGSEGVRLAVELSPDVILMDLVMEGMDGIEATKQICRELSDPKIIV
LTSFIDDDKVYPVIEAGALSYLLKTSKAAEIADAIRAASKGEPKLESKVAGKVLSRLRHSGENALPHESLTKRELEILCL
IAEGKTNKEIGEELFITIKTVKTHITNILSKLDVSDRTQAAVYAHRNHLVN

Nucleotide


Download         Length: 636 bp        

>NTDB_id=865469 WHO22_RS17960 WP_003243201.1 3393936..3394571(-) (vraR) [Bacillus subtilis isolate FELIX_MS513]
GTGATTCGAGTATTATTGATTGATGATCATGAAATGGTCAGAATGGGGCTCGCGGCTTTTTTGGAGGCGCAGCCCGATAT
TGAAGTCATCGGCGAAGCATCGGACGGCAGCGAAGGTGTTCGGCTTGCTGTGGAACTGTCGCCTGATGTCATTTTAATGG
ACCTTGTCATGGAGGGCATGGATGGCATTGAAGCTACAAAGCAAATTTGCCGGGAGCTTTCCGACCCGAAAATTATTGTG
CTCACTAGCTTCATTGATGATGACAAAGTGTACCCGGTTATTGAAGCTGGCGCGCTCAGCTATCTGTTGAAAACCTCAAA
AGCGGCAGAAATCGCCGATGCCATCCGCGCCGCAAGCAAGGGAGAGCCGAAGCTGGAGTCAAAAGTGGCGGGAAAAGTAT
TATCCAGGCTGCGCCACTCAGGTGAAAACGCGCTCCCGCATGAATCGCTTACAAAACGGGAGCTCGAAATACTCTGCCTG
ATCGCAGAAGGAAAGACAAACAAAGAAATAGGCGAGGAACTGTTTATTACGATTAAAACAGTCAAAACACATATTACGAA
TATTTTATCAAAGCTGGATGTCAGTGACCGGACGCAGGCGGCGGTGTACGCACACCGAAATCATCTCGTGAATTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O32197

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.857

99.526

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

38.565

100

0.408