Detailed information NTG0865404

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: WHO22_RS08280
• Genome accession: NZ_CP148122
• Coordinates: 1572282..1573307 (+)
• Length: 341 a.a.
• NCBI ID: WP_003245451.1
• Uniprot ID: O34470
• Organism: Bacillus subtilis isolate FELIX_MS513
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1567282..1578307

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WHO22_RS08245	ylbE	1567582..1567821 (+)	240	WP_003232231.1	YlbE-like family protein	-
WHO22_RS08250	ylbF	1567937..1568386 (+)	450	WP_003221370.1	regulatory iron-sulfur-containing complex subunit RicF	Regulator
WHO22_RS08255	ylbG	1568441..1568713 (+)	273	WP_009967171.1	YlbG family protein	-
WHO22_RS08260	rsmD	1569036..1569590 (+)	555	WP_003232227.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
WHO22_RS08265	coaD	1569595..1570080 (+)	486	WP_003245283.1	pantetheine-phosphate adenylyltransferase	-
WHO22_RS08270	spoVV	1570091..1571317 (-)	1227	WP_003245492.1	dipicolinic acid transporter SpoVV	-
WHO22_RS08275	ylbK	1571498..1572280 (+)	783	WP_003232221.1	patatin family protein	-
WHO22_RS08280	sepM	1572282..1573307 (+)	1026	WP_003245451.1	protease DdcP	Regulator
WHO22_RS08285	ylbM	1573324..1574571 (-)	1248	WP_003244707.1	nucleotidyltransferase	-
WHO22_RS08290	-	1574568..1574753 (-)	186	WP_003232215.1	hypothetical protein	-
WHO22_RS08295	ylbN	1574781..1575299 (+)	519	WP_003232214.1	DUF177 domain-containing protein	-
WHO22_RS08300	rpmF	1575321..1575500 (+)	180	WP_003154457.1	50S ribosomal protein L32	-
WHO22_RS08305	gerR	1575646..1576227 (+)	582	WP_003232210.1	sporulation specific transcriptional regulator GerR	-
WHO22_RS08310	ylbP	1576284..1576766 (-)	483	WP_003244940.1	N-acetyltransferase	-
WHO22_RS08315	-	1576926..1577822 (+)	897	WP_003232206.1	2-dehydropantoate 2-reductase	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37651.23 Da
• Isoelectric Point: 6.5347

>NTDB_id=865404 WHO22_RS08280 WP_003245451.1 1572282..1573307(+) (sepM) [Bacillus subtilis isolate FELIX_MS513]
MLRKKHFSWMLVILILIAVLSFIKLPYYITKPGEATELASLIKVEGGYPEKGSLSLMTVKVGPANPFTYVWAKMHPYYEI
VPDESIKEEGESDKEYMKRQLQMMKSSQENAVIAAYQKAGKKVSYSFNGIYASSVVENMPAKGKIEVGDKIISADGKNYQ
SAEKLIDYISSKKAGDKVTLKIEREEKEKRVTLTLKQFPDEPDRAGIGVSLYTDRNVKVEPDIDFEIENIGGPSAGLMMS
LEIYNQLTKPDETKGYDIAGTGTIDVDGKVGPIGGIDQKVVAADKAGKDIFFAPNQNGASNSDYKNAVKTAKDIDSNMKI
VPVDTMQDAIDYLNKLKAKST

Nucleotide

• Length: 1026 bp

>NTDB_id=865404 WHO22_RS08280 WP_003245451.1 1572282..1573307(+) (sepM) [Bacillus subtilis isolate FELIX_MS513]
TTGCTACGTAAAAAACATTTTAGCTGGATGCTCGTCATCCTCATACTGATCGCCGTTTTATCATTTATAAAACTTCCATA
CTATATTACAAAACCGGGAGAAGCGACAGAGCTTGCTTCATTGATAAAAGTGGAGGGAGGCTACCCGGAAAAAGGAAGTC
TGTCCTTAATGACTGTTAAAGTGGGACCGGCTAATCCATTTACATATGTGTGGGCAAAGATGCACCCTTATTATGAAATT
GTTCCTGATGAGAGCATTAAGGAGGAAGGCGAATCAGATAAGGAGTATATGAAAAGACAGCTCCAAATGATGAAAAGCTC
GCAAGAAAATGCGGTTATAGCCGCCTATCAAAAGGCAGGAAAAAAAGTCAGCTATTCCTTTAACGGCATATACGCAAGCT
CAGTTGTAGAAAACATGCCGGCAAAAGGGAAAATAGAAGTCGGTGATAAAATCATCAGCGCAGACGGCAAAAACTATCAG
TCTGCTGAAAAGCTGATTGATTATATCAGCAGCAAAAAAGCGGGAGATAAAGTCACGTTAAAGATCGAAAGAGAAGAAAA
AGAAAAGCGTGTCACCCTTACGTTAAAACAATTTCCTGATGAGCCGGATCGGGCAGGAATCGGAGTTTCGCTTTATACAG
ACAGAAACGTGAAGGTAGAGCCTGATATTGATTTTGAAATCGAAAATATTGGCGGCCCGTCAGCAGGGTTAATGATGTCC
CTTGAAATCTATAATCAGCTGACAAAACCAGACGAAACAAAAGGCTACGATATTGCGGGAACAGGTACGATTGATGTTGA
CGGAAAAGTAGGCCCGATCGGCGGCATTGATCAAAAAGTCGTCGCCGCAGACAAAGCCGGAAAAGACATTTTCTTCGCGC
CAAATCAAAACGGCGCCAGCAATTCCGATTATAAGAACGCAGTAAAAACAGCAAAAGATATTGATTCAAATATGAAGATT
GTGCCTGTTGATACCATGCAGGATGCGATTGATTATTTGAATAAGCTGAAAGCGAAAAGCACCTGA

Domains

Predicted by InterProScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-331)

• Peptidase family M50 (Peptidase_M50) (59-220)

• PDZ domain (PDZ_2) (128-195)

3D structure

• PDB: 2KJP

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	39.143	100	0.402