Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   WHO37_RS09090 Genome accession   NZ_CP148116
Coordinates   1888244..1888900 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli isolate FELIX_MS508     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1883244..1893900
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHO37_RS09055 dcyD 1884123..1885109 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  WHO37_RS09060 tcyL 1885124..1885792 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  WHO37_RS09065 tcyN 1885789..1886541 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WHO37_RS09070 sdiA 1886771..1887493 (+) 723 WP_001152715.1 transcriptional regulator SdiA -
  WHO37_RS09075 yecF 1887561..1887785 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  WHO37_RS09080 yecU 1887772..1887948 (-) 177 WP_000590347.1 protein YecU -
  WHO37_RS09085 - 1888031..1888102 (-) 72 Protein_1771 transcriptional regulator -
  WHO37_RS09090 letA 1888244..1888900 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  WHO37_RS09095 uvrC 1888897..1890729 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  WHO37_RS09100 pgsA 1890786..1891334 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WHO37_RS09120 yecA 1891984..1892649 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=864894 WHO37_RS09090 WP_000611335.1 1888244..1888900(+) (letA) [Escherichia coli isolate FELIX_MS508]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=864894 WHO37_RS09090 WP_000611335.1 1888244..1888900(+) (letA) [Escherichia coli isolate FELIX_MS508]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486