Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   WHO32_RS05240 Genome accession   NZ_CP148112
Coordinates   1009388..1010032 (+) Length   214 a.a.
NCBI ID   WP_003245647.1    Uniprot ID   O07528
Organism   Bacillus subtilis isolate FELIX_MS504     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1004388..1015032
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHO32_RS05225 glpD 1004559..1006226 (+) 1668 WP_003233382.1 glycerol-3-phosphate dehydrogenase -
  WHO32_RS05230 pgcA 1006358..1008103 (+) 1746 WP_003244986.1 phosphoglucomutase -
  WHO32_RS05235 yhcY 1008252..1009391 (+) 1140 WP_003245750.1 two-component system sensor histidine kinase YhcY -
  WHO32_RS05240 vraR 1009388..1010032 (+) 645 WP_003245647.1 two-component system response regulator YhcZ Regulator
  WHO32_RS05245 yhdA 1010029..1010553 (+) 525 WP_003244703.1 FMN-dependent NADPH-azoreductase -
  WHO32_RS05250 yhdB 1010568..1010810 (-) 243 WP_003233373.1 YhdB family protein -
  WHO32_RS05255 yhdC 1011011..1011334 (+) 324 WP_003233371.1 YqzG/YhdC family protein -
  WHO32_RS05260 lytF 1011376..1012842 (-) 1467 WP_003244874.1 peptidoglycan endopeptidase LytF -
  WHO32_RS05265 nsrR 1012995..1013435 (-) 441 WP_003245378.1 nitric oxide-sensing transcriptional repressor NsrR -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24022.59 Da        Isoelectric Point: 6.3034

>NTDB_id=864576 WHO32_RS05240 WP_003245647.1 1009388..1010032(+) (vraR) [Bacillus subtilis isolate FELIX_MS504]
MKIVIADDHHVVRKGLRFFFATQDDIEVVGEAATGLEALRVIEETKPDLVLMDLSMPEMDGIQAIKKAIQQFPDTNIIVL
TSYSDQEHVIPALQAGAKAYQLKDTEPEELVKTRQVHGGEYKLSTAIMPHVLTHMKNQHDPEKEKYYQLTRREKDVLTEI
ANGKSNKEIAAALFISEKTVKTHVSNLLAKLEVADRTQAALFAVKYNLNGEISK

Nucleotide


Download         Length: 645 bp        

>NTDB_id=864576 WHO32_RS05240 WP_003245647.1 1009388..1010032(+) (vraR) [Bacillus subtilis isolate FELIX_MS504]
ATGAAAATTGTCATTGCTGATGATCATCATGTTGTCAGAAAGGGTCTGCGTTTTTTCTTTGCCACCCAGGATGATATTGA
AGTCGTCGGAGAAGCTGCAACTGGATTAGAAGCCCTCCGTGTCATCGAAGAGACAAAGCCGGATCTTGTGCTAATGGATT
TGTCTATGCCCGAGATGGACGGCATTCAAGCCATTAAAAAAGCAATACAGCAATTTCCGGATACGAATATCATTGTGCTG
ACGAGCTACTCTGATCAGGAGCACGTCATCCCCGCGCTTCAGGCAGGCGCGAAGGCGTATCAATTAAAGGATACGGAGCC
CGAGGAATTGGTGAAAACACGACAAGTGCATGGTGGCGAATACAAGCTTTCTACAGCTATTATGCCCCATGTGCTGACAC
ATATGAAAAATCAGCACGACCCGGAAAAAGAAAAATACTATCAATTAACTAGAAGGGAAAAAGACGTTCTGACTGAAATA
GCGAACGGGAAAAGCAATAAAGAAATCGCAGCAGCCTTGTTTATTTCAGAAAAAACAGTAAAAACCCATGTATCGAATCT
TTTAGCAAAACTTGAAGTGGCCGATCGCACGCAAGCAGCGCTTTTCGCAGTGAAATATAACCTGAATGGAGAGATCTCAA
AATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O07528

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.976

97.664

0.439
  degU Bacillus subtilis subsp. subtilis str. 168

38.428

100

0.411