Detailed information NTG0864062

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: Q7624_RS09315
• Genome accession: NZ_CP131709
• Coordinates: 1804672..1805709 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727280.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 2016S11-245
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1799672..1810709

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7624_RS09290 (Q7624_09265)	-	1800411..1801742 (-)	1332	WP_000390039.1	hemolysin family protein	-
Q7624_RS09295 (Q7624_09270)	endA	1802033..1802857 (-)	825	WP_001036785.1	DNA-entry nuclease EndA	Machinery gene
Q7624_RS09300 (Q7624_09275)	-	1802896..1803084 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
Q7624_RS09305 (Q7624_09280)	murA	1803077..1804360 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
Q7624_RS09310 (Q7624_09285)	-	1804384..1804614 (-)	231	WP_000615437.1	DUF1146 family protein	-
Q7624_RS09315 (Q7624_09290)	sepM	1804672..1805709 (-)	1038	WP_000727280.1	SepM family pheromone-processing serine protease	Regulator
Q7624_RS09320 (Q7624_09295)	coaD	1805693..1806181 (-)	489	WP_001280766.1	pantetheine-phosphate adenylyltransferase	-
Q7624_RS09325 (Q7624_09300)	rsmD	1806171..1806710 (-)	540	WP_000706960.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
Q7624_RS09330 (Q7624_09305)	asnA	1806775..1807767 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
Q7624_RS09335 (Q7624_09310)	-	1807879..1808562 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
Q7624_RS09340 (Q7624_09315)	-	1808618..1809358 (-)	741	WP_000152701.1	RNA methyltransferase	-
Q7624_RS09345 (Q7624_09320)	-	1809392..1809670 (+)	279	WP_001174613.1	acylphosphatase	-
Q7624_RS09350 (Q7624_09325)	yidC	1809748..1810674 (+)	927	WP_000835948.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37567.60 Da
• Isoelectric Point: 5.0724

>NTDB_id=864062 Q7624_RS09315 WP_000727280.1 1804672..1805709(-) (sepM) [Streptococcus pneumoniae strain 2016S11-245]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFTPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=864062 Q7624_RS09315 WP_000727280.1 1804672..1805709(-) (sepM) [Streptococcus pneumoniae strain 2016S11-245]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTACTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.649	99.13	0.591