Detailed information
Bioinformatically predicted
Overview
| Name | comM | Type | Regulator |
| Locus tag | Q7624_RS09085 | Genome accession | NZ_CP131709 |
| Coordinates | 1758982..1759602 (-) | Length | 206 a.a. |
| NCBI ID | WP_000839909.1 | Uniprot ID | A0A098Z2X2 |
| Organism | Streptococcus pneumoniae strain 2016S11-245 | ||
| Function | fratricide immunity (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1747437..1791355 | 1758982..1759602 | within | 0 |
Gene organization within MGE regions
Location: 1747437..1791355
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| Q7624_RS09015 (Q7624_08990) | - | 1747734..1748285 (-) | 552 | WP_001111247.1 | hypothetical protein | - |
| Q7624_RS09020 (Q7624_08995) | - | 1748275..1748472 (-) | 198 | WP_000890144.1 | hypothetical protein | - |
| Q7624_RS09025 (Q7624_09000) | - | 1748476..1749270 (-) | 795 | WP_001101215.1 | hypothetical protein | - |
| Q7624_RS09030 (Q7624_09005) | - | 1749678..1750103 (-) | 426 | WP_000204068.1 | hypothetical protein | - |
| Q7624_RS09035 (Q7624_09010) | - | 1750232..1750591 (-) | 360 | WP_000749821.1 | hypothetical protein | - |
| Q7624_RS09040 (Q7624_09015) | - | 1750637..1750843 (-) | 207 | WP_000366087.1 | hypothetical protein | - |
| Q7624_RS09045 (Q7624_09020) | - | 1750830..1750991 (-) | 162 | WP_000289348.1 | helix-turn-helix transcriptional regulator | - |
| Q7624_RS09050 (Q7624_09025) | lytA | 1751350..1752306 (-) | 957 | WP_000405240.1 | N-acetylmuramoyl-L-alanine amidase LytA | - |
| Q7624_RS09055 (Q7624_09030) | - | 1752682..1754052 (-) | 1371 | WP_001036271.1 | MATE family efflux transporter | - |
| Q7624_RS09060 (Q7624_09035) | recA | 1754359..1755525 (-) | 1167 | WP_001085462.1 | recombinase RecA | Machinery gene |
| Q7624_RS09065 (Q7624_09040) | cinA | 1755580..1756836 (-) | 1257 | WP_000642704.1 | competence/damage-inducible protein A | Machinery gene |
| Q7624_RS09070 (Q7624_09045) | - | 1756921..1757937 (-) | 1017 | WP_000239278.1 | LCP family protein | - |
| Q7624_RS09075 (Q7624_09050) | - | 1757945..1758463 (-) | 519 | WP_000455536.1 | GNAT family N-acetyltransferase | - |
| Q7624_RS09080 (Q7624_09055) | tsaE | 1758453..1758896 (-) | 444 | WP_000288230.1 | tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE | - |
| Q7624_RS09085 (Q7624_09060) | comM | 1758982..1759602 (-) | 621 | WP_000839909.1 | hypothetical protein | Regulator |
| Q7624_RS09090 (Q7624_09065) | - | 1759908..1760771 (-) | 864 | WP_001093609.1 | helix-turn-helix transcriptional regulator | - |
| Q7624_RS09095 (Q7624_09070) | - | 1760962..1761132 (+) | 171 | WP_001227863.1 | PhrA family quorum-sensing system peptide | - |
| Q7624_RS09100 (Q7624_09075) | - | 1761534..1761848 (+) | 315 | WP_000420682.1 | YdcP family protein | - |
| Q7624_RS09105 (Q7624_09080) | - | 1761864..1762250 (+) | 387 | WP_000985015.1 | YdcP family protein | - |
| Q7624_RS09110 (Q7624_09085) | - | 1762279..1763664 (+) | 1386 | WP_000813494.1 | FtsK/SpoIIIE domain-containing protein | - |
| Q7624_RS09115 (Q7624_09090) | - | 1763667..1763819 (+) | 153 | WP_000879507.1 | hypothetical protein | - |
| Q7624_RS09120 (Q7624_09095) | mobT | 1763842..1765104 (+) | 1263 | WP_001814870.1 | MobT family relaxase | - |
| Q7624_RS09125 (Q7624_09100) | - | 1765049..1765261 (+) | 213 | WP_029645760.1 | peptide-binding protein | - |
| Q7624_RS09130 (Q7624_09105) | - | 1765310..1765393 (+) | 84 | WP_001814874.1 | 23S rRNA methyltransferase attenuation leader peptide | - |
| Q7624_RS09135 (Q7624_09110) | erm(B) | 1765518..1766255 (+) | 738 | WP_001038795.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) | - |
| Q7624_RS09140 (Q7624_09115) | - | 1766512..1767759 (-) | 1248 | WP_000019067.1 | ISL3 family transposase | - |
| Q7624_RS09145 (Q7624_09120) | - | 1767939..1768160 (+) | 222 | WP_001009056.1 | hypothetical protein | - |
| Q7624_RS09150 (Q7624_09125) | - | 1768277..1768774 (+) | 498 | WP_000342539.1 | antirestriction protein ArdA | - |
| Q7624_RS09155 (Q7624_09130) | - | 1768863..1769255 (+) | 393 | WP_000723888.1 | conjugal transfer protein | - |
| Q7624_RS09160 (Q7624_09135) | - | 1769239..1771686 (+) | 2448 | WP_000331160.1 | ATP-binding protein | - |
| Q7624_RS09165 (Q7624_09140) | - | 1771689..1773866 (+) | 2178 | WP_001814875.1 | membrane protein | - |
| Q7624_RS09170 (Q7624_09145) | - | 1773863..1774864 (+) | 1002 | WP_000769868.1 | bifunctional lysozyme/C40 family peptidase | - |
| Q7624_RS09175 (Q7624_09150) | - | 1774861..1775793 (+) | 933 | WP_001224318.1 | conjugal transfer protein | - |
| Q7624_RS09180 (Q7624_09155) | - | 1776038..1776154 (+) | 117 | WP_001814923.1 | tetracycline resistance determinant leader peptide | - |
| Q7624_RS09185 (Q7624_09160) | tet(M) | 1776170..1778089 (+) | 1920 | WP_000691729.1 | tetracycline resistance ribosomal protection protein Tet(M) | - |
| Q7624_RS09190 (Q7624_09165) | - | 1778453..1778698 (+) | 246 | WP_001813542.1 | hypothetical protein | - |
| Q7624_RS09195 (Q7624_09170) | - | 1778695..1779030 (+) | 336 | WP_000806926.1 | hypothetical protein | - |
| Q7624_RS09200 (Q7624_09175) | - | 1779043..1779411 (+) | 369 | WP_000567222.1 | hypothetical protein | - |
| Q7624_RS09205 (Q7624_09180) | - | 1779398..1779697 (+) | 300 | WP_001072467.1 | DUF5960 family protein | - |
| Q7624_RS09210 (Q7624_09185) | msr(D) | 1779815..1781278 (-) | 1464 | WP_000420313.1 | ABC-F type ribosomal protection protein Msr(D) | - |
| Q7624_RS09215 (Q7624_09190) | mef(A) | 1781398..1782615 (-) | 1218 | WP_000417519.1 | macrolide efflux MFS transporter Mef(A) | - |
| Q7624_RS09220 (Q7624_09195) | - | 1783001..1783171 (-) | 171 | WP_000873143.1 | hypothetical protein | - |
| Q7624_RS09225 (Q7624_09200) | - | 1783693..1783884 (+) | 192 | WP_001860868.1 | cysteine-rich KTR domain-containing protein | - |
| Q7624_RS09230 (Q7624_09205) | - | 1783944..1784297 (-) | 354 | WP_001227347.1 | helix-turn-helix transcriptional regulator | - |
| Q7624_RS09235 (Q7624_09210) | - | 1784802..1785224 (+) | 423 | WP_000804885.1 | sigma-70 family RNA polymerase sigma factor | - |
| Q7624_RS09240 (Q7624_09215) | - | 1785221..1785451 (+) | 231 | WP_000857133.1 | helix-turn-helix domain-containing protein | - |
| Q7624_RS09245 (Q7624_09220) | - | 1785677..1785928 (-) | 252 | WP_001845478.1 | hypothetical protein | - |
| Q7624_RS09250 (Q7624_09225) | - | 1785912..1786115 (+) | 204 | WP_000814511.1 | excisionase | - |
| Q7624_RS09255 (Q7624_09230) | - | 1786197..1787414 (+) | 1218 | WP_001291561.1 | tyrosine-type recombinase/integrase | - |
| Q7624_RS09260 (Q7624_09235) | - | 1788305..1790320 (+) | 2016 | WP_000732395.1 | DUF1430 domain-containing protein | - |
| Q7624_RS09265 (Q7624_09240) | - | 1790322..1790954 (+) | 633 | WP_000571425.1 | ABC transporter ATP-binding protein | - |
Sequence
Protein
Download Length: 206 a.a. Molecular weight: 23540.66 Da Isoelectric Point: 10.1254
>NTDB_id=864060 Q7624_RS09085 WP_000839909.1 1758982..1759602(-) (comM) [Streptococcus pneumoniae strain 2016S11-245]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYTGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYTGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF
Nucleotide
Download Length: 621 bp
>NTDB_id=864060 Q7624_RS09085 WP_000839909.1 1758982..1759602(-) (comM) [Streptococcus pneumoniae strain 2016S11-245]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATACTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATACTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG
Domains
No domain identified.
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comM | Streptococcus pneumoniae D39 |
99.515 |
100 |
0.995 |
| comM | Streptococcus pneumoniae R6 |
99.515 |
100 |
0.995 |
| comM | Streptococcus pneumoniae TIGR4 |
99.515 |
100 |
0.995 |
| comM | Streptococcus mitis NCTC 12261 |
38.462 |
94.66 |
0.364 |
| comM | Streptococcus mitis SK321 |
38.462 |
94.66 |
0.364 |