Detailed information NTG0863987

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: Q7625_RS09725
• Genome accession: NZ_CP131708
• Coordinates: 1911078..1912088 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 2016C10-332
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1906078..1917088

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7625_RS09700 (Q7625_09685)	-	1906144..1907358 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
Q7625_RS09705 (Q7625_09690)	-	1907514..1907807 (-)	294	WP_000977368.1	hypothetical protein	-
Q7625_RS09710 (Q7625_09695)	-	1907969..1908421 (+)	453	WP_000079148.1	universal stress protein	-
Q7625_RS09715 (Q7625_09700)	-	1908456..1909844 (-)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
Q7625_RS09720 (Q7625_09705)	-	1909910..1910872 (+)	963	WP_001124777.1	asparaginase	-
Q7625_RS09725 (Q7625_09710)	ccpA	1911078..1912088 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
Q7625_RS09730 (Q7625_09715)	-	1912513..1913112 (-)	600	WP_000866719.1	response regulator transcription factor	-
Q7625_RS09735 (Q7625_09720)	-	1913114..1914211 (-)	1098	WP_000893500.1	sensor histidine kinase	-
Q7625_RS09740 (Q7625_09725)	-	1914211..1914948 (-)	738	WP_000832916.1	ABC transporter permease	-
Q7625_RS09745 (Q7625_09730)	-	1914950..1915834 (-)	885	WP_001055978.1	ABC transporter ATP-binding protein	-
Q7625_RS09750 (Q7625_09735)	-	1915821..1916015 (-)	195	WP_000820189.1	hypothetical protein	-
Q7625_RS09755 (Q7625_09740)	-	1916012..1916218 (-)	207	Protein_1910	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=863987 Q7625_RS09725 WP_000990607.1 1911078..1912088(-) (ccpA) [Streptococcus pneumoniae strain 2016C10-332]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=863987 Q7625_RS09725 WP_000990607.1 1911078..1912088(-) (ccpA) [Streptococcus pneumoniae strain 2016C10-332]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568