Detailed information NTG0863986

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: Q7625_RS09570
• Genome accession: NZ_CP131708
• Coordinates: 1883640..1884677 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727280.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 2016C10-332
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1878640..1889677

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7625_RS09545 (Q7625_09530)	-	1879441..1880772 (-)	1332	WP_000390046.1	hemolysin family protein	-
Q7625_RS09550 (Q7625_09535)	endA	1881001..1881825 (-)	825	WP_001036779.1	DNA-entry nuclease EndA	Machinery gene
Q7625_RS09555 (Q7625_09540)	-	1881864..1882052 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
Q7625_RS09560 (Q7625_09545)	murA	1882045..1883328 (-)	1284	WP_000358033.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
Q7625_RS09565 (Q7625_09550)	-	1883352..1883582 (-)	231	WP_000615437.1	DUF1146 family protein	-
Q7625_RS09570 (Q7625_09555)	sepM	1883640..1884677 (-)	1038	WP_000727280.1	SepM family pheromone-processing serine protease	Regulator
Q7625_RS09575 (Q7625_09560)	coaD	1884661..1885149 (-)	489	WP_001280766.1	pantetheine-phosphate adenylyltransferase	-
Q7625_RS09580 (Q7625_09565)	rsmD	1885139..1885678 (-)	540	WP_000706960.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
Q7625_RS09585 (Q7625_09570)	asnA	1885743..1886735 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
Q7625_RS09590 (Q7625_09575)	-	1886847..1887530 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
Q7625_RS09595 (Q7625_09580)	-	1887586..1888326 (-)	741	WP_000152701.1	RNA methyltransferase	-
Q7625_RS09600 (Q7625_09585)	-	1888360..1888638 (+)	279	WP_001174613.1	acylphosphatase	-
Q7625_RS09605 (Q7625_09590)	yidC	1888716..1889642 (+)	927	WP_000835948.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37567.60 Da
• Isoelectric Point: 5.0724

>NTDB_id=863986 Q7625_RS09570 WP_000727280.1 1883640..1884677(-) (sepM) [Streptococcus pneumoniae strain 2016C10-332]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFTPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=863986 Q7625_RS09570 WP_000727280.1 1883640..1884677(-) (sepM) [Streptococcus pneumoniae strain 2016C10-332]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTACTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.649	99.13	0.591