Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   Q7625_RS07515 Genome accession   NZ_CP131708
Coordinates   1485763..1486995 (-) Length   410 a.a.
NCBI ID   WP_000106354.1    Uniprot ID   A0A4M6D977
Organism   Streptococcus pneumoniae strain 2016C10-332     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1480763..1491995
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7625_RS07485 (Q7625_07475) - 1480950..1481918 (+) 969 WP_000080998.1 NAD(P)/FAD-dependent oxidoreductase -
  Q7625_RS07490 (Q7625_07480) whiA 1481952..1482863 (-) 912 WP_000011276.1 DNA-binding protein WhiA -
  Q7625_RS07495 (Q7625_07485) - 1482860..1483837 (-) 978 WP_001231086.1 YvcK family protein -
  Q7625_RS07500 (Q7625_07490) rapZ 1483834..1484724 (-) 891 WP_341922155.1 RNase adapter RapZ -
  Q7625_RS07505 (Q7625_07495) - 1484776..1485156 (-) 381 WP_001140420.1 RidA family protein -
  Q7625_RS07510 (Q7625_07500) yihA 1485167..1485754 (-) 588 WP_247932137.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  Q7625_RS07515 (Q7625_07505) clpX 1485763..1486995 (-) 1233 WP_000106354.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  Q7625_RS07520 (Q7625_07510) - 1487027..1487197 (-) 171 WP_000442276.1 hypothetical protein -
  Q7625_RS07525 (Q7625_07515) - 1487197..1487703 (-) 507 WP_000162437.1 dihydrofolate reductase -
  Q7625_RS07530 (Q7625_07520) - 1487833..1488351 (-) 519 WP_000229857.1 Dps family protein -
  Q7625_RS07535 (Q7625_07525) lytC 1488849..1490354 (-) 1506 WP_012386833.1 choline binding-anchored murein hydrolase LytC -
  Q7625_RS07540 (Q7625_07530) tpiA 1490392..1491150 (-) 759 WP_341922165.1 triose-phosphate isomerase -
  Q7625_RS07545 (Q7625_07535) - 1491248..1491925 (-) 678 WP_000221614.1 DnaD domain-containing protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45713.24 Da        Isoelectric Point: 4.4550

>NTDB_id=863967 Q7625_RS07515 WP_000106354.1 1485763..1486995(-) (clpX) [Streptococcus pneumoniae strain 2016C10-332]
MSTNRKNDMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKEAVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=863967 Q7625_RS07515 WP_000106354.1 1485763..1486995(-) (clpX) [Streptococcus pneumoniae strain 2016C10-332]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAGCCAAGAAGAAGTACAAAAAATAAT
CGCTGGCAACAATGCCTTTATTTGTAATGAATGCGTGGAGCTAGCTCAAGAAATTATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTACCAAAACCAATCGAACTCCTCCATATCTTGAACCACTATGTAATCGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAATCATTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATCTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTGCCTTTTGCGATCGCAGATGCGACAGCTCTTACTGAGGCTGGTTATGTAGGTGAGGATGTGGAAAAC
ATTCTCCTCAAACTTTTGCAGGCTGCTGACTTTAACATTGAACGTGCAGAGCGTGGCATTATTTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAACGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCTCTTCTCAAGA
TTATCGAGGGAACCGTTGCCAGCGTACCGCCTCAAGGTGGACGTAAACATCCACAACAAGAGATGATTCAAGTGGATACT
AAAAATATCCTCTTCATCGTGGGTGGTGCCTTTGATGGCATTGAAGAAATCGTCAAACAACGTCTTGGAGAAAAAGTCAT
CGGATTTGGTCAAAATAATAAAGCGATTGATGAAAACAGCTCATACATGCAAGAAATCATCGCAGAAGATATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCAGTCTTTGCTGCTCTTGAGCAATTGACAGTTGACGACTTGGTGCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTCAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCCAATAAAGCCATCGAACGGAAGACAGGAGCGCGTGGTCTTCGCTCGATTATCGAAG
AAACCATGCTAGATGTCATGTTTGAAGTACCGAGTCAGGAAAATGTGAAATTGGTCCGCATCACAAAAGAAGCTGTCGAT
GGAACGGATAAACCAATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4M6D977

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.829

100

0.868
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.463

98.049

0.563