Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   Q7626_RS01710 Genome accession   NZ_CP131707
Coordinates   336146..336835 (+) Length   229 a.a.
NCBI ID   WP_000518008.1    Uniprot ID   A0A0B7KUQ5
Organism   Streptococcus pneumoniae strain 2018C08-270     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 331146..341835
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7626_RS01685 (Q7626_01680) gpsB 331255..331584 (+) 330 WP_000146522.1 cell division regulator GpsB -
  Q7626_RS01695 (Q7626_01690) - 332070..333227 (+) 1158 WP_000726418.1 class I SAM-dependent RNA methyltransferase -
  Q7626_RS01700 (Q7626_01695) mapZ 333240..334634 (+) 1395 WP_000039290.1 mid-cell-anchored protein MapZ -
  Q7626_RS01705 (Q7626_01700) gndA 334710..336134 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  Q7626_RS01710 (Q7626_01705) covR 336146..336835 (+) 690 WP_000518008.1 response regulator transcription factor Regulator
  Q7626_RS01715 (Q7626_01710) cbpC 336933..337952 (+) 1020 WP_088777294.1 choline-binding protein CbpC -
  Q7626_RS01720 (Q7626_01715) - 338070..339302 (-) 1233 WP_000765686.1 MFS transporter -
  Q7626_RS01725 - 339831..340188 (-) 358 Protein_336 lanthionine synthetase LanC family protein -
  Q7626_RS01730 (Q7626_01725) - 340851..341180 (+) 330 WP_000196977.1 transposase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26914.21 Da        Isoelectric Point: 6.9836

>NTDB_id=863865 Q7626_RS01710 WP_000518008.1 336146..336835(+) (covR) [Streptococcus pneumoniae strain 2018C08-270]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=863865 Q7626_RS01710 WP_000518008.1 336146..336835(+) (covR) [Streptococcus pneumoniae strain 2018C08-270]
ATGGGGAAACGGATTTTATTACTTGAAAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAACTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGTCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7KUQ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467