Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   Q7627_RS09820 Genome accession   NZ_CP131706
Coordinates   1899526..1900479 (-) Length   317 a.a.
NCBI ID   WP_000345126.1    Uniprot ID   A0A0F7YBB9
Organism   Streptococcus pneumoniae strain 2018N21-288     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1894526..1905479
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7627_RS09790 (Q7627_09770) - 1895287..1895910 (-) 624 WP_000932658.1 hypothetical protein -
  Q7627_RS09795 (Q7627_09775) jag 1895961..1896947 (-) 987 WP_000260018.1 RNA-binding cell elongation regulator Jag/EloR -
  Q7627_RS09800 (Q7627_09780) - 1896966..1897790 (-) 825 WP_000727904.1 membrane protein insertase YidC -
  Q7627_RS09805 (Q7627_09785) rnpA 1897765..1898136 (-) 372 WP_000739246.1 ribonuclease P protein component -
  Q7627_RS09810 (Q7627_09790) - 1898153..1898284 (-) 132 WP_000768904.1 hypothetical protein -
  Q7627_RS09815 (Q7627_09795) - 1898285..1899475 (-) 1191 WP_000167765.1 acetate kinase -
  Q7627_RS09820 (Q7627_09800) comYH 1899526..1900479 (-) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  Q7627_RS09825 (Q7627_09805) - 1900540..1901132 (-) 593 Protein_1910 methyltransferase domain-containing protein -
  Q7627_RS09830 (Q7627_09810) comGG/cglG 1901235..1901681 (-) 447 WP_001809944.1 competence type IV pilus minor pilin ComGG Machinery gene
  Q7627_RS09835 (Q7627_09815) comGF/cglF 1901659..1902120 (-) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  Q7627_RS09840 (Q7627_09820) comGE/cglE 1902083..1902385 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  Q7627_RS09845 (Q7627_09825) comGD/cglD 1902348..1902782 (-) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  Q7627_RS09850 (Q7627_09830) comGC/cglC 1902745..1903068 (-) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  Q7627_RS09855 (Q7627_09835) comGB/cglB 1903070..1904086 (-) 1017 WP_078130737.1 competence type IV pilus assembly protein ComGB Machinery gene
  Q7627_RS09860 (Q7627_09840) comGA/cglA/cilD 1904034..1904975 (-) 942 WP_000249536.1 competence type IV pilus ATPase ComGA Machinery gene
  Q7627_RS09865 (Q7627_09845) - 1905051..1905416 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35714.87 Da        Isoelectric Point: 4.2434

>NTDB_id=863836 Q7627_RS09820 WP_000345126.1 1899526..1900479(-) (comYH) [Streptococcus pneumoniae strain 2018N21-288]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=863836 Q7627_RS09820 WP_000345126.1 1899526..1900479(-) (comYH) [Streptococcus pneumoniae strain 2018N21-288]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTACTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F7YBB9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536