Detailed information NTG0863838

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: Q7627_RS09835
• Genome accession: NZ_CP131706
• Coordinates: 1901659..1902120 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250531.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 2018N21-288
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1896659..1907120

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7627_RS09800 (Q7627_09780)	-	1896966..1897790 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
Q7627_RS09805 (Q7627_09785)	rnpA	1897765..1898136 (-)	372	WP_000739246.1	ribonuclease P protein component	-
Q7627_RS09810 (Q7627_09790)	-	1898153..1898284 (-)	132	WP_000768904.1	hypothetical protein	-
Q7627_RS09815 (Q7627_09795)	-	1898285..1899475 (-)	1191	WP_000167765.1	acetate kinase	-
Q7627_RS09820 (Q7627_09800)	comYH	1899526..1900479 (-)	954	WP_000345126.1	class I SAM-dependent methyltransferase	Machinery gene
Q7627_RS09825 (Q7627_09805)	-	1900540..1901132 (-)	593	Protein_1910	methyltransferase domain-containing protein	-
Q7627_RS09830 (Q7627_09810)	comGG/cglG	1901235..1901681 (-)	447	WP_001809944.1	competence type IV pilus minor pilin ComGG	Machinery gene
Q7627_RS09835 (Q7627_09815)	comGF/cglF	1901659..1902120 (-)	462	WP_000250531.1	competence type IV pilus minor pilin ComGF	Machinery gene
Q7627_RS09840 (Q7627_09820)	comGE/cglE	1902083..1902385 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
Q7627_RS09845 (Q7627_09825)	comGD/cglD	1902348..1902782 (-)	435	WP_033606693.1	competence type IV pilus minor pilin ComGD	Machinery gene
Q7627_RS09850 (Q7627_09830)	comGC/cglC	1902745..1903068 (-)	324	WP_000738628.1	comG operon protein ComGC	Machinery gene
Q7627_RS09855 (Q7627_09835)	comGB/cglB	1903070..1904086 (-)	1017	WP_078130737.1	competence type IV pilus assembly protein ComGB	Machinery gene
Q7627_RS09860 (Q7627_09840)	comGA/cglA/cilD	1904034..1904975 (-)	942	WP_000249536.1	competence type IV pilus ATPase ComGA	Machinery gene
Q7627_RS09865 (Q7627_09845)	-	1905051..1905416 (-)	366	WP_000286415.1	DUF1033 family protein	-
Q7627_RS09870 (Q7627_09850)	-	1905567..1906625 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17849.37 Da
• Isoelectric Point: 6.4832

>NTDB_id=863838 Q7627_RS09835 WP_000250531.1 1901659..1902120(-) (comGF/cglF) [Streptococcus pneumoniae strain 2018N21-288]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=863838 Q7627_RS09835 WP_000250531.1 1901659..1902120(-) (comGF/cglF) [Streptococcus pneumoniae strain 2018N21-288]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGTAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae D39	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae R6	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae TIGR4	95.425	100	0.954
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915