Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   WAC27_RS22330 Genome accession   NZ_CP148034
Coordinates   4507849..4508505 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain NH-21     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4502849..4513505
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WAC27_RS22300 (WAC27_22300) yecA 4504100..4504765 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  WAC27_RS22320 (WAC27_22320) pgsA 4505415..4505963 (-) 549 WP_032278420.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WAC27_RS22325 (WAC27_22325) uvrC 4506020..4507852 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  WAC27_RS22330 (WAC27_22330) letA 4507849..4508505 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  WAC27_RS22335 (WAC27_22335) - 4508647..4508763 (+) 117 WP_001302039.1 hypothetical protein -
  WAC27_RS22340 (WAC27_22340) yecU 4508801..4508977 (+) 177 WP_000590344.1 protein YecU -
  WAC27_RS22345 (WAC27_22345) yecF 4508964..4509188 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  WAC27_RS22350 (WAC27_22350) sdiA 4509256..4509978 (-) 723 WP_338850481.1 transcriptional regulator SdiA -
  WAC27_RS22355 (WAC27_22355) tcyN 4510208..4510960 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WAC27_RS22360 (WAC27_22360) tcyL 4510957..4511625 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  WAC27_RS22365 (WAC27_22365) dcyD 4511640..4512626 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=863699 WAC27_RS22330 WP_000611328.1 4507849..4508505(-) (letA) [Escherichia coli strain NH-21]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=863699 WAC27_RS22330 WP_000611328.1 4507849..4508505(-) (letA) [Escherichia coli strain NH-21]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482