Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   WGK59_RS05120 Genome accession   NZ_CP148002
Coordinates   1011461..1013290 (+) Length   609 a.a.
NCBI ID   WP_014326539.1    Uniprot ID   -
Organism   Haemophilus influenzae strain AR2427     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1006461..1018290
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WGK59_RS05105 (WGK59_05105) msbA 1007646..1009409 (+) 1764 WP_014326542.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  WGK59_RS05110 (WGK59_05110) lpxK 1009482..1010480 (+) 999 WP_014326541.1 tetraacyldisaccharide 4'-kinase -
  WGK59_RS05115 (WGK59_05115) kdsB 1010551..1011315 (+) 765 WP_014326540.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  WGK59_RS05120 (WGK59_05120) uvrC 1011461..1013290 (+) 1830 WP_014326539.1 excinuclease ABC subunit UvrC Machinery gene
  WGK59_RS05125 (WGK59_05125) - 1013388..1014101 (+) 714 WP_014326538.1 TerC family protein -
  WGK59_RS05130 (WGK59_05130) gshAB 1014276..1016564 (+) 2289 WP_014326537.1 bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB -
  WGK59_RS05135 (WGK59_05135) - 1017017..1017310 (+) 294 Protein_963 IS3 family transposase -
  WGK59_RS05140 (WGK59_05140) - 1017339..1017683 (-) 345 Protein_964 zinc ribbon domain-containing protein YjdM -

Sequence

Protein


Download         Length: 609 a.a.        Molecular weight: 69564.49 Da        Isoelectric Point: 9.3088

>NTDB_id=863604 WGK59_RS05120 WP_014326539.1 1011461..1013290(+) (uvrC) [Haemophilus influenzae strain AR2427]
MFNYKKFLADVSHEPGVYRMYDDKDQVIYVGKAKDLKKRLSSYFRKNLSSKKTEALVASIHHIDTMLTSSETEALLLEHN
FIKLYQPRYNVLLRDDKSYPFILLTKERHPRITSYRGSKKFAGEYFGPYPHAGAVRETLSLLQKLFPVRQCENSVYSNRS
RPCLQYQIGRCSAPCVQGYVSDEEYNQQVELARLFLQGKDQLVLDYLIGKMEQASRNLDFEQAARYRDQIQAVRSVIEKQ
FVSNERLDDMDIMSIAYQHGLACVQVMFIRQGKVLGNRSYFPKVPANTDLSELTETFVGQFYLQGHQGRSIPNSIIVDRQ
LAEKSELEQLLSKQAGRKVTIQESVKGDKSKYLQLAQVNAKAALNVQLKQSSRMSERYQALCDLLNLPEIKRMECFDISH
TMGNQTVASCVVFNQEGPLKSDYRRFNIEGITGGDDYAAMEQALQKRYERDLEEDKIPDIIFIDGGKGQLNRALNVFQHL
QVKWDKNRPHLIGVAKGVDRRAGQEVLIISKQDREIHLPDDSLALHLIQHIRDESHNNAISGHRKKRQKAFTQSGLETIE
GVGAKRRQALLKYLGGLQGVKKATLDEIASVPGISLKLAETIFETLKND

Nucleotide


Download         Length: 1830 bp        

>NTDB_id=863604 WGK59_RS05120 WP_014326539.1 1011461..1013290(+) (uvrC) [Haemophilus influenzae strain AR2427]
ATGTTCAATTACAAAAAATTCCTCGCTGATGTCTCTCACGAACCTGGTGTTTATCGTATGTATGACGATAAAGATCAGGT
TATTTATGTTGGGAAAGCAAAGGATCTAAAAAAACGTCTTTCAAGCTATTTTCGTAAAAATCTGAGTAGTAAAAAAACAG
AGGCGTTGGTGGCATCAATTCATCATATTGACACCATGCTAACTTCATCTGAAACGGAAGCTTTACTGCTAGAGCATAAT
TTTATCAAGCTTTATCAGCCTCGCTATAACGTATTATTGCGTGATGATAAATCCTATCCATTTATTTTATTAACCAAAGA
ACGCCATCCAAGAATCACGTCCTATCGTGGGTCTAAAAAATTTGCGGGTGAATATTTCGGGCCCTATCCTCACGCAGGCG
CCGTGCGTGAAACTTTATCGCTTTTACAAAAACTTTTCCCTGTTCGACAATGTGAAAATTCCGTTTATTCCAACCGCTCT
CGTCCTTGTTTACAATATCAAATTGGGCGTTGTTCTGCGCCTTGTGTACAGGGATATGTTTCCGATGAAGAATATAATCA
GCAAGTTGAATTAGCCCGCTTATTTTTACAAGGCAAAGATCAACTGGTGTTAGATTATTTAATCGGGAAAATGGAGCAGG
CAAGCAGAAATTTAGATTTTGAACAGGCGGCTCGTTATCGTGATCAGATTCAGGCGGTGCGTTCGGTTATTGAAAAACAA
TTTGTATCCAATGAACGTTTAGATGATATGGATATTATGTCCATCGCTTATCAACACGGTTTAGCCTGTGTACAGGTGAT
GTTTATTCGTCAAGGAAAAGTGCTAGGCAATCGCAGTTATTTCCCAAAAGTCCCCGCCAATACGGATTTATCGGAACTTA
CCGAAACTTTTGTAGGGCAATTTTATTTACAAGGTCATCAAGGGCGAAGTATCCCAAATAGTATTATTGTTGATCGTCAA
TTAGCTGAAAAATCAGAGCTTGAGCAACTTCTTAGCAAGCAAGCGGGCAGAAAAGTGACGATTCAAGAAAGTGTAAAAGG
CGATAAGAGTAAATACTTACAGCTCGCACAAGTTAATGCTAAAGCGGCTTTAAATGTACAACTTAAACAATCTTCACGAA
TGTCAGAGCGTTATCAAGCGTTGTGTGATCTGTTAAATCTCCCTGAAATTAAGCGTATGGAGTGTTTCGATATAAGCCAC
ACGATGGGAAATCAAACGGTAGCATCTTGTGTTGTCTTTAATCAAGAAGGCCCACTGAAATCTGATTATCGTCGTTTTAA
TATTGAAGGCATTACTGGCGGGGATGATTATGCTGCAATGGAACAAGCGTTGCAGAAACGTTATGAGCGTGATTTAGAAG
AAGATAAAATTCCCGATATTATTTTTATTGATGGTGGAAAAGGGCAATTAAATCGTGCGCTGAACGTGTTCCAACATCTT
CAAGTAAAATGGGATAAAAATAGACCGCACTTAATTGGCGTGGCAAAAGGTGTGGATCGTCGAGCAGGGCAGGAAGTACT
GATCATCAGCAAACAAGACCGCGAAATTCATTTGCCTGATGATAGTTTGGCATTGCATTTGATTCAACACATCCGTGATG
AAAGTCATAATAACGCAATAAGCGGACACCGTAAAAAACGTCAAAAAGCCTTTACACAAAGCGGTTTAGAAACTATTGAA
GGTGTGGGCGCTAAACGTCGTCAGGCTTTACTGAAATATCTTGGTGGTTTACAAGGTGTGAAAAAGGCGACCTTAGATGA
AATAGCCTCTGTACCGGGAATTTCCCTTAAACTTGCTGAAACGATTTTTGAAACGCTCAAAAACGATTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(210-234)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-540)

GIY-YIG catalytic domain (GIY-YIG)

(15-90)

Helix-hairpin-helix domain (HHH_5)

(556-607)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.815

97.701

0.369
  uvrC Streptococcus pneumoniae R6

37.479

97.701

0.366
  uvrC Streptococcus pneumoniae D39

37.479

97.701

0.366