Detailed information NTG0863450

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q7639_RS09165
• Genome accession: NZ_CP131661
• Coordinates: 1897028..1898071 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 2010C08-173
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1892028..1903071

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7639_RS09135 (Q7639_09125)	-	1892449..1893705 (-)	1257	WP_158109059.1	aminopeptidase	-
Q7639_RS09140 (Q7639_09130)	-	1893708..1893908 (-)	201	WP_000180460.1	DUF1128 family protein	-
Q7639_RS09145 (Q7639_09135)	-	1894055..1894519 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q7639_RS09150 (Q7639_09140)	-	1894526..1894801 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q7639_RS09155 (Q7639_09145)	-	1895079..1896296 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
Q7639_RS09160 (Q7639_09150)	vraR	1896409..1897038 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
Q7639_RS09165 (Q7639_09155)	vraS	1897028..1898071 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q7639_RS09170 (Q7639_09160)	liaF	1898068..1898769 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
Q7639_RS09175 (Q7639_09165)	-	1898784..1899170 (-)	387	WP_001110182.1	hypothetical protein	-
Q7639_RS09180 (Q7639_09170)	map	1899387..1900145 (-)	759	WP_000636145.1	type I methionyl aminopeptidase	-
Q7639_RS09185 (Q7639_09175)	-	1900674..1901660 (+)	987	WP_000999712.1	aromatic acid exporter family protein	-
Q7639_RS09190 (Q7639_09180)	-	1901849..1902262 (-)	414	WP_025174370.1	hypothetical protein	-
Q7639_RS09195 (Q7639_09185)	-	1902291..1902401 (-)	111	WP_014937049.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=863450 Q7639_RS09165 WP_001017131.1 1897028..1898071(-) (vraS) [Staphylococcus aureus strain 2010C08-173]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=863450 Q7639_RS09165 WP_001017131.1 1897028..1898071(-) (vraS) [Staphylococcus aureus strain 2010C08-173]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTTCTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAATTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAATTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1