Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   WAB15_RS13460 Genome accession   NZ_CP147982
Coordinates   2986138..2986815 (+) Length   225 a.a.
NCBI ID   WP_399147929.1    Uniprot ID   A0ABZ2QK63
Organism   Streptomyces sp. BP-8     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2981138..2991815
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WAB15_RS13440 (WAB15_13415) - 2981445..2982104 (+) 660 WP_399147933.1 TetR/AcrR family transcriptional regulator -
  WAB15_RS13445 (WAB15_13420) - 2982317..2983531 (+) 1215 WP_407286364.1 alpha/beta hydrolase -
  WAB15_RS13450 (WAB15_13425) - 2983733..2984614 (+) 882 WP_407286365.1 DUF4429 domain-containing protein -
  WAB15_RS13455 (WAB15_13430) - 2984750..2986141 (+) 1392 WP_407286366.1 sensor histidine kinase -
  WAB15_RS13460 (WAB15_13435) vraR 2986138..2986815 (+) 678 WP_399147929.1 response regulator Regulator
  WAB15_RS13465 (WAB15_13440) - 2986962..2988128 (+) 1167 WP_407286367.1 alpha/beta hydrolase -
  WAB15_RS13470 (WAB15_13445) - 2988186..2989424 (+) 1239 WP_399147927.1 acyltransferase -
  WAB15_RS13475 (WAB15_13450) - 2989482..2990498 (-) 1017 WP_407286368.1 aldo/keto reductase -
  WAB15_RS13480 (WAB15_13455) - 2990506..2990988 (-) 483 WP_399147925.1 MerR family transcriptional regulator -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 24389.21 Da        Isoelectric Point: 5.4021

>NTDB_id=863387 WAB15_RS13460 WP_399147929.1 2986138..2986815(+) (vraR) [Streptomyces sp. BP-8]
MTTRVIIVDDQAMVRAGFAALLAAQSDIDVVGDAPDGAQGVELSRRTHPDVVLMDVRMPEMDGLEAARRLLDPPIGVTHR
PKVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLISAVRVVAAGEALLAPSVTRRLIADFARRPVPRKDRASLRLNGL
TPRETEVLELIARGLSNQEIAEALILAEQTVKTHIGRVLAKLELRDRAQAVIFAYESGLVAPGER

Nucleotide


Download         Length: 678 bp        

>NTDB_id=863387 WAB15_RS13460 WP_399147929.1 2986138..2986815(+) (vraR) [Streptomyces sp. BP-8]
ATGACCACCCGCGTGATCATCGTCGACGACCAGGCCATGGTGCGCGCGGGGTTCGCCGCGCTGCTCGCGGCGCAGAGCGA
CATCGATGTGGTGGGCGACGCGCCGGACGGTGCGCAGGGGGTGGAGCTGAGCCGCCGGACGCACCCCGATGTGGTGCTGA
TGGACGTCCGGATGCCGGAGATGGACGGGCTGGAGGCGGCCCGCAGGCTGCTCGATCCGCCCATCGGCGTCACCCATCGC
CCGAAGGTGCTGATGCTGACCACCTTCGACGTCGACGACTACGTCTACGAAGCGCTGCGCGCGGGCGCCTCGGGGTTCCT
GCTCAAGGACGCCCCGCCGGCCGATCTGATCTCCGCGGTCCGGGTCGTGGCGGCCGGTGAGGCGCTGCTGGCGCCGTCCG
TGACCCGACGGCTGATCGCCGACTTCGCCCGGCGGCCGGTGCCCCGCAAGGACCGGGCCTCGCTCCGGCTGAACGGGCTG
ACGCCGCGGGAGACGGAGGTGCTGGAGCTGATCGCCCGGGGACTGTCGAACCAGGAGATCGCCGAGGCGCTGATCCTCGC
CGAGCAGACCGTGAAGACCCATATCGGCCGGGTGCTCGCCAAGTTGGAGCTGCGGGACCGGGCACAGGCCGTGATCTTCG
CCTACGAGTCGGGGCTGGTGGCCCCCGGGGAGCGGTAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(160-214)

Response regulator receiver domain (Response_reg)

(5-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

42.986

98.222

0.422
  degU Bacillus subtilis subsp. subtilis str. 168

37.168

100

0.373