Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   WAB15_RS10375 Genome accession   NZ_CP147982
Coordinates   2285310..2285957 (-) Length   215 a.a.
NCBI ID   WP_399150032.1    Uniprot ID   A0ABZ2QLU7
Organism   Streptomyces sp. BP-8     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2280310..2290957
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WAB15_RS10340 (WAB15_10315) - 2280682..2281620 (-) 939 WP_399150038.1 SPFH domain-containing protein -
  WAB15_RS10345 (WAB15_10320) - 2281724..2282137 (-) 414 WP_399150048.1 NfeD family protein -
  WAB15_RS10350 (WAB15_10325) - 2282265..2283077 (-) 813 WP_407286039.1 ABC transporter ATP-binding protein -
  WAB15_RS10355 (WAB15_10330) - 2283167..2283979 (+) 813 WP_407286040.1 hypothetical protein -
  WAB15_RS10360 (WAB15_10335) - 2284085..2284330 (-) 246 WP_407286041.1 chaplin -
  WAB15_RS10365 (WAB15_10340) - 2284479..2284724 (-) 246 WP_407286042.1 chaplin -
  WAB15_RS10370 (WAB15_10345) - 2284878..2285120 (-) 243 WP_407286043.1 chaplin -
  WAB15_RS10375 (WAB15_10350) vraR 2285310..2285957 (-) 648 WP_399150032.1 response regulator Regulator
  WAB15_RS10380 (WAB15_10355) - 2285950..2287107 (-) 1158 WP_399150031.1 GAF domain-containing sensor histidine kinase -
  WAB15_RS10385 (WAB15_10360) - 2287302..2288177 (+) 876 WP_407286044.1 SDR family NAD(P)-dependent oxidoreductase -
  WAB15_RS10390 (WAB15_10365) - 2288174..2289328 (+) 1155 WP_407286045.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  WAB15_RS10395 (WAB15_10370) - 2289345..2290061 (+) 717 WP_399150028.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 215 a.a.        Molecular weight: 22886.06 Da        Isoelectric Point: 4.9660

>NTDB_id=863382 WAB15_RS10375 WP_399150032.1 2285310..2285957(-) (vraR) [Streptomyces sp. BP-8]
MADTGSIRVLLVDDHQVVRRGLRTFLEVQDDIEVVGEASDGAEGVAAAEQLGPDVVLMDVKMPGMDGIEALRKLRELNNP
ARVLVVTSFTEQRTVVPALRAGAAGYVYKDIDPEALAAAIRSVHAGHVLLQPEVAGALLSQDEGNGGQGRGTSLTERESE
VLGLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGIGA

Nucleotide


Download         Length: 648 bp        

>NTDB_id=863382 WAB15_RS10375 WP_399150032.1 2285310..2285957(-) (vraR) [Streptomyces sp. BP-8]
GTGGCTGACACCGGCTCAATCCGCGTACTCCTGGTCGACGACCACCAGGTCGTCCGCCGGGGCCTGCGGACGTTCCTGGA
GGTCCAGGACGACATCGAGGTGGTGGGGGAGGCCTCCGACGGGGCCGAGGGCGTCGCCGCCGCCGAGCAACTGGGTCCGG
ACGTCGTCCTGATGGACGTCAAGATGCCCGGGATGGACGGCATCGAGGCGCTCCGCAAGCTGCGCGAACTGAACAACCCC
GCACGGGTGCTGGTGGTGACGAGCTTCACCGAGCAGCGCACCGTCGTCCCGGCGCTACGCGCGGGCGCGGCCGGCTACGT
CTACAAGGACATCGACCCCGAGGCGCTGGCCGCCGCCATCCGCTCCGTCCACGCCGGCCATGTCCTGCTGCAGCCCGAGG
TGGCCGGCGCGCTGCTCTCCCAGGACGAGGGCAACGGCGGCCAGGGGCGCGGCACCTCGCTCACGGAACGCGAGAGCGAG
GTGCTGGGCCTGATCGCGGACGGCCGCTCCAACCGCGAGATCGCCCGTGCGCTGGTGCTGTCCGAGAAGACCGTCAAGAC
CCATGTCTCCAACATTCTCATGAAGCTCGACCTCGCCGACCGGACGCAGGCGGCGCTGTGGGCCGTCCGGCACGGCATCG
GGGCCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(9-121)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.55

98.14

0.437
  degU Bacillus subtilis subsp. subtilis str. 168

37.387

100

0.386