Detailed information NTG0863281

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: WFE12_RS08285
• Genome accession: NZ_CP147877
• Coordinates: 1574180..1575205 (+)
• Length: 341 a.a.
• NCBI ID: WP_003245451.1
• Uniprot ID: O34470
• Organism: Bacillus subtilis subsp. subtilis str. 168
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1569180..1580205

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WFE12_RS08250	ylbE	1569480..1569719 (+)	240	WP_003232231.1	YlbE-like family protein	-
WFE12_RS08255	ylbF	1569835..1570284 (+)	450	WP_003221370.1	regulatory iron-sulfur-containing complex subunit RicF	Regulator
WFE12_RS08260	ylbG	1570339..1570611 (+)	273	WP_009967171.1	YlbG family protein	-
WFE12_RS08265	rsmD	1570934..1571488 (+)	555	WP_003232227.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
WFE12_RS08270	coaD	1571493..1571978 (+)	486	WP_003245283.1	pantetheine-phosphate adenylyltransferase	-
WFE12_RS08275	spoVV	1571989..1573215 (-)	1227	WP_003245492.1	dipicolinic acid transporter SpoVV	-
WFE12_RS08280	ylbK	1573396..1574178 (+)	783	WP_003232221.1	patatin family protein	-
WFE12_RS08285	sepM	1574180..1575205 (+)	1026	WP_003245451.1	protease DdcP	Regulator
WFE12_RS08290	ylbM	1575222..1576469 (-)	1248	WP_003244707.1	nucleotidyltransferase	-
WFE12_RS08295	-	1576466..1576651 (-)	186	WP_003232215.1	hypothetical protein	-
WFE12_RS08300	ylbN	1576679..1577197 (+)	519	WP_003232214.1	DUF177 domain-containing protein	-
WFE12_RS08305	rpmF	1577219..1577398 (+)	180	WP_003154457.1	50S ribosomal protein L32	-
WFE12_RS08310	gerR	1577544..1578125 (+)	582	WP_003232210.1	sporulation specific transcriptional regulator GerR	-
WFE12_RS08315	ylbP	1578182..1578664 (-)	483	WP_003244940.1	N-acetyltransferase	-
WFE12_RS08320	-	1578824..1579720 (+)	897	WP_003232206.1	2-dehydropantoate 2-reductase	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37651.23 Da
• Isoelectric Point: 6.5347

>NTDB_id=863281 WFE12_RS08285 WP_003245451.1 1574180..1575205(+) (sepM) [Bacillus subtilis subsp. subtilis str. 168]
MLRKKHFSWMLVILILIAVLSFIKLPYYITKPGEATELASLIKVEGGYPEKGSLSLMTVKVGPANPFTYVWAKMHPYYEI
VPDESIKEEGESDKEYMKRQLQMMKSSQENAVIAAYQKAGKKVSYSFNGIYASSVVENMPAKGKIEVGDKIISADGKNYQ
SAEKLIDYISSKKAGDKVTLKIEREEKEKRVTLTLKQFPDEPDRAGIGVSLYTDRNVKVEPDIDFEIENIGGPSAGLMMS
LEIYNQLTKPDETKGYDIAGTGTIDVDGKVGPIGGIDQKVVAADKAGKDIFFAPNQNGASNSDYKNAVKTAKDIDSNMKI
VPVDTMQDAIDYLNKLKAKST

Nucleotide

• Length: 1026 bp

>NTDB_id=863281 WFE12_RS08285 WP_003245451.1 1574180..1575205(+) (sepM) [Bacillus subtilis subsp. subtilis str. 168]
TTGCTACGTAAAAAACATTTTAGCTGGATGCTCGTCATCCTCATACTGATCGCCGTTTTATCATTTATAAAACTTCCATA
CTATATTACAAAACCGGGAGAAGCGACAGAGCTTGCTTCATTGATAAAAGTGGAGGGAGGCTACCCGGAAAAAGGAAGTC
TGTCCTTAATGACTGTTAAAGTGGGACCGGCTAATCCATTTACATATGTGTGGGCAAAGATGCACCCTTATTATGAAATT
GTTCCTGATGAGAGCATTAAGGAGGAAGGCGAATCAGATAAGGAGTATATGAAAAGACAGCTCCAAATGATGAAAAGCTC
GCAAGAAAATGCGGTTATAGCCGCCTATCAAAAGGCAGGAAAAAAAGTCAGCTATTCCTTTAACGGCATATACGCAAGCT
CAGTTGTAGAAAACATGCCGGCAAAAGGGAAAATAGAAGTCGGTGATAAAATCATCAGCGCAGACGGCAAAAACTATCAG
TCTGCTGAAAAGCTGATTGATTATATCAGCAGCAAAAAAGCGGGAGATAAAGTCACGTTAAAGATCGAAAGAGAAGAAAA
AGAAAAGCGTGTCACCCTTACGTTAAAACAATTTCCTGATGAGCCGGATCGGGCAGGAATCGGAGTTTCGCTTTATACAG
ACAGAAACGTGAAGGTAGAGCCTGATATTGATTTTGAAATCGAAAATATTGGCGGCCCGTCAGCAGGGTTAATGATGTCC
CTTGAAATCTATAATCAGCTGACAAAACCAGACGAAACAAAAGGCTACGATATTGCGGGAACAGGTACGATTGATGTTGA
CGGAAAAGTAGGCCCGATCGGCGGCATTGATCAAAAAGTCGTCGCCGCAGACAAAGCCGGAAAAGACATTTTCTTCGCGC
CAAATCAAAACGGCGCCAGCAATTCCGATTATAAGAACGCAGTAAAAACAGCAAAAGATATTGATTCAAATATGAAGATT
GTGCCTGTTGATACCATGCAGGATGCGATTGATTATTTGAATAAGCTGAAAGCGAAAAGCACCTGA

Domains

Predicted by InterProScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-331)

• Peptidase family M50 (Peptidase_M50) (59-220)

• PDZ domain (PDZ_2) (128-195)

3D structure

• PDB: 2KJP

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	39.143	100	0.402