Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   WFE12_RS05250 Genome accession   NZ_CP147877
Coordinates   1011217..1011861 (+) Length   214 a.a.
NCBI ID   WP_003245647.1    Uniprot ID   O07528
Organism   Bacillus subtilis subsp. subtilis str. 168     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1006217..1016861
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WFE12_RS05235 glpD 1006388..1008055 (+) 1668 WP_003233382.1 glycerol-3-phosphate dehydrogenase -
  WFE12_RS05240 pgcA 1008187..1009932 (+) 1746 WP_003244986.1 phosphoglucomutase -
  WFE12_RS05245 yhcY 1010081..1011220 (+) 1140 WP_003245750.1 two-component system sensor histidine kinase YhcY -
  WFE12_RS05250 vraR 1011217..1011861 (+) 645 WP_003245647.1 two-component system response regulator YhcZ Regulator
  WFE12_RS05255 yhdA 1011858..1012382 (+) 525 WP_003244703.1 FMN-dependent NADPH-azoreductase -
  WFE12_RS05260 yhdB 1012397..1012639 (-) 243 WP_003233373.1 YhdB family protein -
  WFE12_RS05265 yhdC 1012840..1013163 (+) 324 WP_003233371.1 YqzG/YhdC family protein -
  WFE12_RS05270 lytF 1013205..1014671 (-) 1467 WP_003244874.1 peptidoglycan endopeptidase LytF -
  WFE12_RS05275 nsrR 1014824..1015264 (-) 441 WP_003245378.1 nitric oxide-sensing transcriptional repressor NsrR -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24022.59 Da        Isoelectric Point: 6.3034

>NTDB_id=863249 WFE12_RS05250 WP_003245647.1 1011217..1011861(+) (vraR) [Bacillus subtilis subsp. subtilis str. 168]
MKIVIADDHHVVRKGLRFFFATQDDIEVVGEAATGLEALRVIEETKPDLVLMDLSMPEMDGIQAIKKAIQQFPDTNIIVL
TSYSDQEHVIPALQAGAKAYQLKDTEPEELVKTRQVHGGEYKLSTAIMPHVLTHMKNQHDPEKEKYYQLTRREKDVLTEI
ANGKSNKEIAAALFISEKTVKTHVSNLLAKLEVADRTQAALFAVKYNLNGEISK

Nucleotide


Download         Length: 645 bp        

>NTDB_id=863249 WFE12_RS05250 WP_003245647.1 1011217..1011861(+) (vraR) [Bacillus subtilis subsp. subtilis str. 168]
ATGAAAATTGTCATTGCTGATGATCATCATGTTGTCAGAAAGGGTCTGCGTTTTTTCTTTGCCACCCAGGATGATATTGA
AGTCGTCGGAGAAGCTGCAACTGGATTAGAAGCCCTCCGTGTCATCGAAGAGACAAAGCCGGATCTTGTGCTAATGGATT
TGTCTATGCCCGAGATGGACGGCATTCAAGCCATTAAAAAAGCAATACAGCAATTTCCGGATACGAATATCATTGTGCTG
ACGAGCTACTCTGATCAGGAGCACGTCATCCCCGCGCTTCAGGCAGGCGCGAAGGCGTATCAATTAAAGGATACGGAGCC
CGAGGAATTGGTGAAAACACGACAAGTGCATGGTGGCGAATACAAGCTTTCTACAGCTATTATGCCCCATGTGCTGACAC
ATATGAAAAATCAGCACGACCCGGAAAAAGAAAAATACTATCAATTAACTAGAAGGGAAAAAGACGTTCTGACTGAAATA
GCGAACGGGAAAAGCAATAAAGAAATCGCAGCAGCCTTGTTTATTTCAGAAAAAACAGTAAAAACCCATGTATCGAATCT
TTTAGCAAAACTTGAAGTGGCCGATCGCACGCAAGCAGCGCTTTTCGCAGTGAAATATAACCTGAATGGAGAGATCTCAA
AATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O07528

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.976

97.664

0.439
  degU Bacillus subtilis subsp. subtilis str. 168

38.428

100

0.411