Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   Q7649_RS09030 Genome accession   NZ_CP131630
Coordinates   1715906..1716301 (-) Length   131 a.a.
NCBI ID   WP_003703428.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain 2018C07-301     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1709663..1722249 1715906..1716301 within 0


Gene organization within MGE regions


Location: 1709663..1722249
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7649_RS08970 (Q7649_09030) - 1709766..1710023 (-) 258 WP_235220045.1 autotransporter outer membrane beta-barrel domain-containing protein -
  Q7649_RS08975 (Q7649_09035) - 1709949..1710110 (+) 162 WP_003700479.1 hypothetical protein -
  Q7649_RS08980 (Q7649_09040) - 1710207..1710869 (-) 663 WP_014580358.1 hypothetical protein -
  Q7649_RS08985 (Q7649_09045) - 1711209..1711454 (-) 246 WP_003689849.1 hypothetical protein -
  Q7649_RS08990 (Q7649_09050) - 1711566..1711994 (+) 429 WP_020997399.1 CopD family protein -
  Q7649_RS08995 (Q7649_09055) - 1712006..1712482 (+) 477 WP_003689851.1 CYTH domain-containing protein -
  Q7649_RS09000 (Q7649_09060) - 1712512..1713000 (-) 489 WP_025455834.1 dihydrofolate reductase -
  Q7649_RS09005 (Q7649_09065) aroG 1713068..1714123 (-) 1056 WP_003689853.1 3-deoxy-7-phosphoheptulonate synthase AroG -
  Q7649_RS09010 (Q7649_09070) - 1714285..1714512 (-) 228 WP_153707886.1 hypothetical protein -
  Q7649_RS09015 (Q7649_09075) - 1714740..1715036 (+) 297 WP_003689859.1 hypothetical protein -
  Q7649_RS09020 (Q7649_09080) - 1715033..1715272 (+) 240 WP_012503951.1 membrane protein -
  Q7649_RS09025 - 1715825..1715972 (+) 148 Protein_1758 peptidase -
  Q7649_RS09030 (Q7649_09085) comE 1715906..1716301 (-) 396 WP_003703428.1 helix-hairpin-helix domain-containing protein Machinery gene
  Q7649_RS09035 (Q7649_09090) - 1716403..1716522 (-) 120 Protein_1760 competence protein ComE -
  Q7649_RS09065 (Q7649_09120) - 1722091..1722249 (-) 159 WP_162488836.1 hypothetical protein -

Sequence

Protein


Download         Length: 131 a.a.        Molecular weight: 13796.61 Da        Isoelectric Point: 10.8790

>NTDB_id=863000 Q7649_RS09030 WP_003703428.1 1715906..1716301(-) (comE) [Neisseria gonorrhoeae strain 2018C07-301]
MSRGGATPYRFLLIRHIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINAASQQELEALPGIGPAKAKAIAEY
RAQNGAFKSVDDLIKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPAVKK

Nucleotide


Download         Length: 396 bp        

>NTDB_id=863000 Q7649_RS09030 WP_003703428.1 1715906..1716301(-) (comE) [Neisseria gonorrhoeae strain 2018C07-301]
TTGAGCCGGGGCGGGGCAACGCCGTACCGGTTTTTGTTAATCCGCCATATCGTCGCAAGATGCGGTTTGTTGTTTGCAAC
CCTTAAAGGAAAAACCATGAAAAAAATGTTTGTATTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAA
ACATCAATGCGGCTTCGCAGCAGGAGCTGGAGGCGCTGCCGGGCATAGGCCCGGCGAAGGCGAAGGCCATTGCGGAATAC
CGCGCGCAAAACGGCGCGTTCAAGTCTGTGGACGATTTGATCAAGGTGAAGGGCATCGGTCCGGCGGTGCTGGCGAAGCT
GAAAGACCAGGCTTCCGTCGGCGCGCCCGCACCAAAAGGCCCCGCCAAACCGGTGCTGCCTGCGGTTAAAAAATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(52-110)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

100

100

1
  comE Neisseria gonorrhoeae MS11

100

100

1
  comE Neisseria gonorrhoeae MS11

100

100

1
  comE Neisseria gonorrhoeae MS11

100

100

1