Detailed information    

insolico Bioinformatically predicted

Overview


Name   pilL   Type   Machinery gene
Locus tag   Q7652_RS02700 Genome accession   NZ_CP131620
Coordinates   520213..520686 (+) Length   157 a.a.
NCBI ID   WP_025455782.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain 2020N08-318     
Function   type IV pilus (predicted from homology)   
DNA binding and uptake

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 521232..558789 520213..520686 flank 546


Gene organization within MGE regions


Location: 520213..558789
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7652_RS02700 (Q7652_02690) pilL 520213..520686 (+) 474 WP_025455782.1 PilX family type IV pilin Machinery gene
  Q7652_RS02705 (Q7652_02695) - 521298..521743 (-) 446 Protein_522 AzlC family ABC transporter permease -
  Q7652_RS02710 (Q7652_02700) dut 521909..522361 (+) 453 WP_003690909.1 dUTP diphosphatase -
  Q7652_RS02715 (Q7652_02705) dapC 522439..523626 (+) 1188 WP_003690911.1 succinyldiaminopimelate transaminase -
  Q7652_RS02720 (Q7652_02710) yaaA 523782..524561 (+) 780 WP_003690913.1 peroxide stress protein YaaA -
  Q7652_RS02735 (Q7652_02725) - 525092..526288 (+) 1197 WP_003704323.1 integrase arm-type DNA-binding domain-containing protein -
  Q7652_RS02740 (Q7652_02730) - 526644..526913 (-) 270 WP_003687928.1 hypothetical protein -
  Q7652_RS02745 (Q7652_02735) - 527108..527791 (-) 684 WP_003687929.1 DUF2786 domain-containing protein -
  Q7652_RS02750 - 528105..528338 (-) 234 Protein_529 hypothetical protein -
  Q7652_RS02755 (Q7652_02745) - 528449..528664 (-) 216 WP_003691538.1 hypothetical protein -
  Q7652_RS02760 (Q7652_02750) - 528716..529207 (-) 492 WP_003691537.1 siphovirus Gp157 family protein -
  Q7652_RS02765 (Q7652_02755) - 529204..529386 (-) 183 WP_003691535.1 hypothetical protein -
  Q7652_RS02770 (Q7652_02760) - 529526..530212 (-) 687 WP_003691532.1 hypothetical protein -
  Q7652_RS02775 (Q7652_02765) - 530281..530442 (-) 162 WP_003691530.1 hypothetical protein -
  Q7652_RS02780 (Q7652_02770) - 530439..530717 (-) 279 WP_003691529.1 hypothetical protein -
  Q7652_RS02785 (Q7652_02775) - 530870..531202 (-) 333 WP_003691528.1 hypothetical protein -
  Q7652_RS02790 (Q7652_02780) - 531343..531630 (-) 288 WP_115067298.1 hypothetical protein -
  Q7652_RS02795 (Q7652_02785) - 531627..532103 (-) 477 WP_002255718.1 hypothetical protein -
  Q7652_RS02800 (Q7652_02790) - 532136..532336 (-) 201 WP_003692842.1 hypothetical protein -
  Q7652_RS02805 (Q7652_02795) - 532534..532947 (-) 414 WP_003687963.1 hypothetical protein -
  Q7652_RS02810 (Q7652_02800) - 532944..533405 (-) 462 WP_003687965.1 helix-turn-helix transcriptional regulator -
  Q7652_RS02815 (Q7652_02805) - 533422..533859 (-) 438 WP_003687967.1 hypothetical protein -
  Q7652_RS02820 (Q7652_02810) - 533974..534690 (-) 717 WP_003687969.1 LexA family transcriptional regulator -
  Q7652_RS02825 (Q7652_02815) - 534759..534995 (+) 237 WP_003687971.1 Cro/CI family transcriptional regulator -
  Q7652_RS02830 (Q7652_02820) - 535075..535230 (+) 156 WP_047923772.1 hypothetical protein -
  Q7652_RS02835 (Q7652_02825) - 535207..535395 (-) 189 WP_047926457.1 hypothetical protein -
  Q7652_RS02840 (Q7652_02830) - 535569..535796 (+) 228 WP_003691442.1 helix-turn-helix domain-containing protein -
  Q7652_RS02845 (Q7652_02835) - 535793..536803 (+) 1011 WP_014580341.1 helix-turn-helix domain-containing protein -
  Q7652_RS02850 (Q7652_02840) - 536815..537588 (+) 774 WP_172761111.1 ATP-binding protein -
  Q7652_RS02855 (Q7652_02845) - 537581..537829 (+) 249 WP_106158912.1 hypothetical protein -
  Q7652_RS02860 (Q7652_02850) - 537904..538398 (+) 495 WP_003691434.1 DUF3310 domain-containing protein -
  Q7652_RS02865 (Q7652_02855) - 538781..538930 (+) 150 WP_106178740.1 hypothetical protein -
  Q7652_RS02870 (Q7652_02860) - 538959..539240 (+) 282 WP_003689109.1 hypothetical protein -
  Q7652_RS02875 (Q7652_02865) - 539231..539668 (+) 438 WP_017147288.1 RusA family crossover junction endodeoxyribonuclease -
  Q7652_RS02880 (Q7652_02870) - 539661..539966 (+) 306 WP_003687981.1 nuclease domain-containing protein -
  Q7652_RS02885 (Q7652_02875) - 539963..540346 (+) 384 WP_003690918.1 recombination protein NinB -
  Q7652_RS02890 (Q7652_02880) - 540337..540855 (+) 519 WP_003687984.1 HNH endonuclease -
  Q7652_RS02895 (Q7652_02885) - 540920..541342 (+) 423 WP_003690919.1 hypothetical protein -
  Q7652_RS02900 (Q7652_02890) - 541342..541881 (+) 540 WP_003690920.1 hypothetical protein -
  Q7652_RS02905 (Q7652_02895) - 541862..543136 (+) 1275 WP_014580143.1 PBSX family phage terminase large subunit -
  Q7652_RS02910 (Q7652_02900) - 543121..545388 (+) 2268 WP_225577699.1 hypothetical protein -
  Q7652_RS02915 (Q7652_02905) - 545625..546821 (+) 1197 WP_003690925.1 hypothetical protein -
  Q7652_RS02920 (Q7652_02910) - 546818..548032 (+) 1215 WP_047954539.1 hypothetical protein -
  Q7652_RS02925 (Q7652_02915) - 550926..554030 (+) 3105 Protein_564 PLxRFG domain-containing protein -
  Q7652_RS02930 (Q7652_02920) - 554012..554749 (+) 738 WP_003690932.1 hypothetical protein -
  Q7652_RS02935 (Q7652_02925) - 554770..556065 (+) 1296 WP_003690933.1 DUF4043 family protein -
  Q7652_RS02940 (Q7652_02930) - 556120..556593 (+) 474 WP_003690936.1 hypothetical protein -
  Q7652_RS02945 (Q7652_02935) - 556599..557084 (+) 486 WP_003687997.1 hypothetical protein -
  Q7652_RS02950 (Q7652_02940) - 557081..557755 (+) 675 WP_003687998.1 hypothetical protein -
  Q7652_RS02955 (Q7652_02945) - 557758..557907 (+) 150 WP_003706419.1 hypothetical protein -
  Q7652_RS02960 (Q7652_02950) - 557944..558789 (-) 846 WP_003690940.1 BRO family protein -

Sequence


Protein


Download         Length: 157 a.a.        Molecular weight: 17506.38 Da        Isoelectric Point: 9.8238

>NTDB_id=862838 Q7652_RS02700 WP_025455782.1 520213..520686(+) (pilL) [Neisseria gonorrhoeae strain 2020N08-318]
MEQKGFTLIEMMIVVTILGIISVIAIPSYQSYIEKGYQSQLYTEMVGINNVLKQFILKNPQDNNQTIKSKLEIFVSGYKM
NPKIAKKYSVSVKFVDAEKPRVYRLVGVPNVGTGYTLSVWMNSVGDGYKCRDAASAKAYKEQLSGDGGCEALSNRKK

Nucleotide


Download         Length: 474 bp        

>NTDB_id=862838 Q7652_RS02700 WP_025455782.1 520213..520686(+) (pilL) [Neisseria gonorrhoeae strain 2020N08-318]
ATGGAACAAAAAGGGTTTACATTGATTGAGATGATGATAGTTGTCACGATACTCGGCATCATCAGCGTCATTGCCATACC
TTCTTATCAGAGTTATATTGAAAAAGGCTATCAGTCCCAGCTTTATACGGAGATGGTCGGTATCAACAATGTTCTCAAAC
AGTTTATTTTGAAAAATCCCCAGGACAATAATCAGACCATCAAGAGCAAACTGGAAATATTTGTCTCAGGCTATAAGATG
AATCCGAAAATTGCCAAAAAATATAGTGTTTCGGTAAAGTTTGTCGATGCGGAAAAACCAAGGGTATACAGGTTGGTCGG
TGTTCCGAACGTGGGGACGGGTTATACCTTGTCGGTATGGATGAACAGCGTGGGCGACGGATACAAATGCCGTGATGCCG
CTTCGGCAAAGGCCTATAAAGAGCAGTTGTCCGGAGACGGTGGTTGTGAAGCCTTATCCAACCGTAAGAAATAG


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilL Neisseria gonorrhoeae MS11

89.172

100

0.892

  pilX Neisseria meningitidis 8013

85.987

100

0.86